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ProteomicsIdentification of a regulatory cascade that activates chloramphenicol biosynthesis in Streptomyces venezuelae
Specialised metabolites made by the genus Streptomyces form the basis of 55% of clinically used antibiotics as well as cancer therapeutics, immunosuppressants and other anti-infectives. Streptomyces venezuelae is a model for the genus because it is fast-growing, sporulates in liquid culture within 2...
ORGANISM(S): Streptomyces venezuelae 
2026-05-21 | PXD064843 | Pride
Streptomyces Venezuelae Orra Wbla 
GenomicsGenes required for aerial growth, cell division, and chromosome segregation are targets of WhiA before sporulation in Streptomyces venezuelae.
WhiA is a highly unusual transcriptional regulator related to a family of eukaryotic homing endonucleases. WhiA is required for sporulation in the filamentous bacterium Streptomyces, but WhiA homologues of unknown function are also found throughout the Gram-positive bacteria. To better understand th...
ORGANISM(S): Streptomyces venezuelae 
2016-05-20 | E-MTAB-4673 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Streptomyces venezuelae wild type and bldN mutant strains
Transcription profiling by array of Streptomyces venezuelae wild type and bldN mutant strains during a time course from 8 to 20 hours, sampling at 2 hour intervals.
ORGANISM(S): Streptomyces venezuelae 
2012-05-15 | E-MEXP-3612 | biostudies-arrayexpress
GenomicsChIP-Seq of the Streptomyces venezuelae regulator BldD and its D116A mutant.
The dimerization and binding of DNA by BldD is affected by its interaction with cyclic di-GMP. The D116A mutant of BldD is partially impaired in its biding of cyclic di-GMP. ChIP-Seq was carried out to determine the difference in the degree of DNA binding by the wild type and D116A mutated BldD in S...
ORGANISM(S): Streptomyces venezuelae 
2017-11-01 | E-MTAB-5328 | biostudies-arrayexpress
ProteomicsThe response regulator MtrA controls development through activation of bldM and whiI in Streptomyces venezuelae
The response regulator MtrA is highly conserved in Streptomyces species where it coordinates antibiotic production with sporulation. Loss of MtrA results in a conditional bald phenotype in S. avermitilis, S. coelicolor and S. venezuelae, where the production of aerial hyphae and spores is blocked on...
ORGANISM(S): Streptomyces venezuelae 
2026-05-21 | PXD069151 | Pride
Mtra Bldm Streptomyces Sporulation Whii Response regulators 
TranscriptomicsTranscriptional profiling of the developmental gene whiA deletion mutant of Streptomyces venezuelae ATCC 10712 at 7 time points from 8 to 20 hours of growth.
WhiA is an unusual transcriptional regulator found in Streptomyces species related to eukaryotic homing endonucleases. It plays a central role in sporulation in these bacteria. The aim of this transcription profiling experiment was to measure genome wide transcript levels in the wild type and the wh...
ORGANISM(S): Streptomyces venezuelae 
2020-12-11 | E-MTAB-9728 | biostudies-arrayexpress
GenomicsStreptomyces venezuelae
Streptomyces venezuelae plasmid-cured strains
PRJNA638164 | ENA
GenomicsIdentifying Lsr2 binding sites in Streptomyces venezuelae
Identifying Lsr2 binding sites in Streptomyces venezuelae
PRJNA475288 | ENA
GenomicsStreptomyces venezuelae ATCC 10712
Streptomyces venezuelae ATCC 10712 genome sequencing project
PRJNA62209 | ENA
GenomicsStreptomyces venezuelae strain:ATCC 15439
Streptomyces venezuelae strain:ATCC 15439 Genome sequencing
PRJNA298854 | ENA
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