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TranscriptomicsDNA profiling of serous ovarian and Fallopian tube carcinomas with array CGH and MLPA
Primary serous ovarian carcinoma (OVCA) and serous Fallopian tube carcinoma (FTC), both belonging to the BRCA-linked tumour spectrum, share many properties and are treated similarly. However, a detailed molecular comparison has been lacking. We hypothesized that comparative genomic studies of serous...
ORGANISM(S): Homo sapiens 
2008-07-08 | E-GEOD-12040 | biostudies-arrayexpress
MetabolomicsAMPK activation induces RALDH+ tolerogenic dendritic cells by rewiring glucose and lipid metabolism.
Dendritic cell (DC) activation and function are underpinned by profound changes in cellular metabolism. Several studies indicate that the ability of DCs to promote tolerance is dependent on catabolic metabolism. Yet the contribution of AMP-activated kinase (AMPK), a central energy sensor promoting c...
2024-08-16 | MTBLS10647 | MetaboLights
ProteomicsProteomic analysis of gliosomes from mouse brain for investigation of glial membrane proteins
Astrocytes are increasingly recognized as crucial contributors to neuronal function at synapses, axons, and somas. Reliable methods that can provide insight into the astrocyte proteins at the neuron-astrocyte functional interface are highly desirable. Here we conducted a mass spectrometry analysis o...
ORGANISM(S): Mus musculus (Mouse) 
2014-11-17 | PXD001375 | Pride
Astrocyte proteins Membrane proteins Gliosome Synaptosome Tripletof 
UnknownLinking Environmental Genotoxins to Neurodegenerative Diseases Through Transcriptional Mutagenesis.
Not available
S-EPMC11545915 | biostudies-literature
TranscriptomicsDietary titanium dioxide (E171) increases systemic ROS levels and alters the colon transcriptome – Evidence from a human dietary intervention study
This study provides critical insights into the adverse effects of titanium dioxide (E171) on human gastrointestinal health and its potential molecular mechanisms of action, marking a significant advancement in food toxicology. Through a human dietary intervention study involving 31 participants cons...
ORGANISM(S): Homo sapiens 
2025-09-30 | E-MTAB-15089 | biostudies-arrayexpress
ProteomicsDeciphering the protein dynamics and molecular determinants of iPSC-derived neurons.
Neuronal development is a multistep process with different regulatory programs that shapes neurons to form dendrites, axons and synapses. To date, knowledge on neuronal development is largely based on murine data and largely restricted to the genomic and transcriptomic level. Advances in stem cell d...
ORGANISM(S): Homo sapiens (Human) 
2020-05-07 | PXD013399 | Pride
Ipsc  human  neuron differentiation  quantitative mass spectrometry  tmt-10plex 
UnknownPredicting missing proteomics values using machine learning: Filling the gap using transcriptomics and other biological features.
Not available
S-EPMC9077535 | biostudies-literature
TranscriptomicsGenetic Aberrations Relate Early and Advanced Stage Ovarian Cancer and are Associated with Survival
BACKGROUND: Because of the distinct clinical presentation of early and advanced stage ovarian cancer, we aim to clarify whether these disease entities are solely separated by time of diagnosis or whether they arise from distinct molecular events. METHODS: Sixteen early and sixteen advanced stage ova...
ORGANISM(S): Homo sapiens 
2012-08-22 | E-GEOD-24418 | biostudies-arrayexpress
UnknownSynthesis of Polystyrene⁻Polyphenylsiloxane Janus Particles through Colloidal Assembly with Unexpected High Selectivity: Mechanistic Insights and Their Application in the Design of Polystyrene Particles with Multiple Polyphenylsiloxane Patches.
Not available
S-EPMC6418681 | biostudies-literature
UnknownGenetic Variation in CNS Myelination and Functional Brain Connectivity in Recombinant Inbred Mice.
Not available
S-EPMC7564997 | biostudies-literature
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