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ProteomicsTranscription complexes in the embryo
In this study, we characterized the composition of TFIID and SAGA complexes in the mouse embryo and analyzed the effect of the depletion of a shared subunit TAF10 during development
ORGANISM(S): Mus musculus (Mouse) 
2017-09-22 | PXD004688 | Pride
Embryo Saga Transcription Tfiid Paraxial mesoderm Somitogenesis 
TranscriptomicsExpression Profiling of Clear cell renal carcinoma
Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment with targeted tyrosine kinase inhibitors (TKIs) is a challenge. Our aim was to identify molecular markers associated with outcome in m-ccRCC patients treated with sunitinib. A Cartes d’Ident...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-MTAB-3267 | biostudies-arrayexpress
MetabolomicsGut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice
Meta-analyses suggest that yogurt consumption reduces type 2 diabetes incidence in humans, but the molecular basis of these observations remains unknown. Here we show that dietary yogurt intake preserves whole-body glucose homeostasis and prevents hepatic insulin resistance and liver steatosis in a ...
2022-02-03 | MTBLS442 | MetaboLights
TranscriptomicsMethylome analysis of epiRIL344 BC1-S1 to BC1-S6 aerial part
DNA methylation profiling in epiRIL344 BC1-S1 to BC1-S6 aerial part (epiRIL344_BC1-S1 - epiRIL344_BC1-S2 - epiRIL344_BC1-S3 - epiRIL344_BC1-S4 - epiRIL344_BC1-S5 - epiRIL344_BC1-S6) Keywords: Genome binding/occupancy profiling by genome tiling array 1 biological replicate in dye-swap - MeDIP-chip
ORGANISM(S): Arabidopsis thaliana 
2012-09-03 | E-GEOD-37285 | biostudies-arrayexpress
TranscriptomicsReconstructing de novo silencing of an active plant retrotransposon: dynamics, mechanisms, biological implications
In plants, maintenance-methylation mediated by METHYLTRANSFERASE-1 (MET1), siRNA-directed de-novo methylation, and chromatin remodeling by DECREASE IN DNA METHYLATION -1 (DDM1) promote transcriptional gene-silencing of transposable elements (TEs). This process is mostly investigated at steady states...
ORGANISM(S): Arabidopsis thaliana 
2013-07-02 | E-GEOD-43412 | biostudies-arrayexpress
GenomicsGenome-wide mapping of Collier in vivo binding sites highlights its hierarchical position in different transcription regulatory networks
Collier, the single Drosophila COE (Collier/EBF/Olf-1) transcription factor, is required in several developmental processes, including head patterning and specification of muscle and neuron identity during embryogenesis. To identify direct Collier (Col) targets in different cell types, we used ChIP-...
ORGANISM(S): Drosophila melanogaster 
2015-08-03 | E-GEOD-67805 | biostudies-arrayexpress
TranscriptomicsPLZF acts as a regulator of cell-cycle genes, restricting hematopoietic stem cell proliferation and prevents hematopoietic stem cell aging.
To uncover gene programs that are regulated by PLZF in the early hematopoietic compartment, we performed micro array-based gene expression analysis of wild-type (WT) or PLZF-mutant (Zbtb16lu/lu) KSLs. DNA-microarrays were used to define and compare the transcriptional profiles of KSL cells isolated...
ORGANISM(S): Mus musculus 
2016-06-29 | E-MTAB-3682 | biostudies-arrayexpress
UnknownWhite blood count, D-dimers, and ferritin levels as predictive factors of pulmonary embolism suspected upon admission in noncritically ill COVID-19 patients: The French multicenter CLOTVID retrospective study.
Not available
S-EPMC8239942 | biostudies-literature
UnknownSotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients.
Not available
S-EPMC11232389 | biostudies-literature
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