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A growing body of evidence supports the importance of T cell responses to protect against severe influenza, promote viral clearance and ensure long-term immunity. Plant-derived virus-like particle (VLP) vaccines bearing influenza hemagglutinin (HA) have been shown to elicit strong humoral and CD4+ T...
ORGANISM(S): Homo sapiens (Human) 
2019-05-28 | PXD010519 | Pride
Human papilloma (HPV) virus-like particle (VLP) vaccines were recently licensed. Though neutralizing antibody titers are thought to be the main effectors of protection against infection, early predictors of long-term efficacy are not yet defined and a comprehensive understanding of innate and adapt...
ORGANISM(S): Homo sapiens 
Immunogenicity and protective efficacy of Marburg virus glycoprotein and virus-like particle-forming mRNA-based vaccines.
Bulk RNA sequencing of CFF-16HBEge cells following plasmid lipofection or virus-like particle transduction
Genomics
Genome-wide screening reveals producer-cell modifications that improve virus-like particle production and delivery potency
Hepatitis C virus (HCV) is the most common chronic blood-borne infection in the United States with the majority of patients becoming chronically infected and a subset (20%) progressing to cirrhosis and hepatocellular carcinoma. Individual variations in immune responses may help define successful res...
ORGANISM(S): Homo sapiens 
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