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TranscriptomicsSingle-cell RNA-seq of human breast tumor samples with exhausted and non-exhausted immune environments
Fresh human breast tumor tissue was dissociated into single cells and viably frozen. Patient samples were annotated as having an ""exhausted"" or ""non-exhausted"" immune environment based on CyTOF characterization of T cell phenotypes (Wagner et al, Cell 2019). 14 samples (7 exhausted, 7 non-exhaus...
ORGANISM(S): Homo sapiens 
2023-08-25 | E-MTAB-10607 | biostudies-arrayexpress
UnknownOrodispersible minitablets of enalapril for use in children with heart failure (LENA): Rationale and protocol for a multicentre pharmacokinetic bridging study and follow-up safety study.
Not available
S-EPMC6586986 | biostudies-literature
UnknownPopulation Pharmacokinetic Analysis of Enalapril and Enalaprilat in Newly Treated Children with Heart Failure: Implications for Safe Dosing of Enalapril (LENA Studies).
Not available
S-EPMC12185616 | biostudies-literature
ProteomicsA Non-interventional Clinical Trial Assessing Immune Responses After Radiofrequency Ablation of Liver Metastases From Colorectal Cancer
HLA ligandome analysis of colorectal adenocarcinoma tissues obtained from liver metastases (mCRC) as well as adjacent non-malignant liver tissues was performed to characterize the natural HLA class I and class II presented ligands on both mCRC and adjacent liver tissue.
ORGANISM(S): Homo sapiens (Human) 
2019-12-11 | PXD015947 | Pride
Neoplasia Cancer Hla-ligandomics Hla Colorectal adenocarcinoma Colon cancer Peptide Hla-restricted peptide Hla-ligand Colon Metastasis 
ProteomicsHB digestion with Pepsin and Napsin
HB digestion with Pepsin and Napsin t=20, 60 and 120 min Analysis by nanoLC-ESI-iTRAP-OrbiTrap
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-10 | MSV000087400 | MassIVE
ProteomicsThe HLA-Ligand-Atlas. A resource of natural HLA ligands presented on benign tissues
The human leukocyte antigen (HLA) complex regulates the adaptive immune response by showcasing the intracellular and extracellular protein content to the immune system. T cells recognize these HLA-presented peptides as self or foreign and can elicit an immune response. In this work, we describe the...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096271 | MassIVE
Genomicsena-DATASET-DKFZ-HIPO-22-04-2016-18:09:52:421-12 - samples
Paired-end RNA sequencing using total RNA from 136 primary lymphoma samples. Sequencing was performed on the Illumina HiSeq2000 with 300bp insert size. The dataset contains FASTQ files.
EGAD00001002056 | EGA
Genomicsena-DATASET-DKFZ-HIPO-22-04-2016-18:03:44:927-11 - samples
Whole exome sequencing from matched tumor-control samples of 121 primary lymphoma samples. Sequencing was performed on Illumina HiSeq2000. The dataset contains FASTQ files.
EGAD00001002055 | EGA
GenomicsDrug-perturbation-based stratification of blood cancer
As new generations of targeted therapies emerge and tumor genome sequencing discovers increasingly comprehensive mutation repertoires, the functional relationships of mutations to tumor phenotypes remain largely unknown. Here, we measured ex vivo sensitivity of 246 blood cancers to 63 drugs alongsid...
EGAS00001001746 | EGA
GenomicsGencode_550K
Lymphoma samples using HumanOmni
EGAD00010000949 | EGA
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