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Algae encode up to five different types of cryptochrome photoreceptors. So far, relatively little is known about the biological functions of the so-called DASH (Drosophila, Arabidopsis, Synechocystis and Homo)-type cryptochromes. The green alga Chlamydomonas reinhardtii encodes two of them. CRY-DASH...
ORGANISM(S): Chlamydomonas reinhardtii CC3269 
2023-10-02 | PXD045811 | Pride
Lysine deacetylases (KDACs) are important regulators of biological processes. KDAC inhibitors (KDACIs) are important tools for basic research and attractive therapeutic candidates, yet their effects on in-vivo acetylation sites are poorly known. Here we obtained acetylation signatures for 19 differe...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2015-02-16 | PXD001377 | Pride
Osteoporosis is the consequence of altered bone metabolism resulting in the systemic reduction of bone strength and increased risk of fragility fractures. MicroRNAs (miRNAs) regulate gene expression on a post-transcriptional level are known to take part in the control of bone formation and bone reso...
ORGANISM(S): Homo sapiens 
Reprogramming of somatic cells into induced pluripotent stem cells (iPSC) is an epigenetic phenomenon. It has been suggested that iPSC retain some tissue-specific memory whereas little is known about inter-individual epigenetic variation of iPSC clones. In this study we have reprogrammed mesenchymal...
ORGANISM(S): Homo sapiens 
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