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UnknownRandomized Phase II Evaluation of Bevacizumab Versus Bevacizumab Plus Fosbretabulin in Recurrent Ovarian, Tubal, or Peritoneal Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study.
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S-EPMC4962710 | biostudies-literature
GenomicsGenome wide localization of chromatin bound NUP98-PHF23 (NP23)
We analyzed the genome wide localization of H3K4me3, H3K27me3 and the NUP98-PHF23 (with V5 tag) fusion protein which binds H3K4me3 via its PHD finger, using ChIP-seq. Results correlated with gene expression profiles. NUP98-PHF23 bound only 1.6% of H3K4me3 marks including Hoxa/b + Meis1. Assess H3K4m...
ORGANISM(S): Mus musculus 
2014-03-06 | E-GEOD-54786 | biostudies-arrayexpress
ProteomicsProteomic analysis of Plasmodium yoelii oocyst sporozoites
Proteomic analysis of Plasmodium yoelii oocyst sporozoites
ORGANISM(S): Plasmodium yoelii yoelii 17XNL 
2019-10-02 | PXD009729 | Pride
Oocyst sporozoites Plasmodium yoelii 
ProteomicsProteomic analysis of Plasmodium falciparum oocyst sporozoites
Proteomic analysis of Plasmodium falciparum oocyst sporozoites
ORGANISM(S): Plasmodium falciparum NF54 
2019-10-02 | PXD009728 | Pride
Plasmodium falciparum Oocyst sporozoite 
TranscriptomicsGene expression study of leukemic and premalignant hematopoietic tissues from NUP98-PHF23 (NP23) mice.
NUP98-PHF23 is oncogenic and results in a Hoxa/b + Meis1 overexpression in NP23 leukemias and in premalignant (clinically healthy) hematopoietic tissues. Gene expression profiles from AML, pre-T LBL and B-ALL were compared to wild type bone marrow, thymus and spleen tissues respectively. Similarly, ...
ORGANISM(S): Mus musculus 
2014-03-06 | E-GEOD-54787 | biostudies-arrayexpress
TranscriptomicsGene Expression and Comparative Genomic Hybridization of Ductal Carcinoma In Situ of the Breast
Background The dramatic increase in incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has given emphasis to the challenges of managing this important clinical entity. Unlike invasive breast cancer, there is no established histopathologic grading sy...
ORGANISM(S): Homo sapiens 
2008-11-24 | E-GEOD-7882 | biostudies-arrayexpress
ProteomicsProteomic analysis of Plasmodium yoelii salivary gland sprozoites
Proteomic analysis of Plasmodium yoelii salivary gland sprozoites
ORGANISM(S): Plasmodium yoelii yoelii 17XNL 
2019-10-02 | PXD009727 | Pride
Plasmodium yoelii Salivary gland sprozoite 
ProteomicsProteomic analysis of Plasmodium falciparum salivary gland sporozoites
Proteomic analysis of Plasmodium falciparum salivary gland sporozoites
ORGANISM(S): Plasmodium falciparum NF54 
2019-10-02 | PXD009726 | Pride
Plasmodium falciparum Malaria Salivary gland sporozoite 
TranscriptomicsA methyl-deviator epigenotype of estrogen-receptor-positive breast carcinoma is associated with malignant biology
We broadly profiled DNA methylation in breast cancers (n=351) and benign parenchyma (n=47) for correspondence with disease phenotype using formalin-fixed paraffin-embedded (FFPE) diagnostic surgical pathology specimens. Exploratory analysis revealed a distinctive primary invasive carcinoma subclass ...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-29428 | biostudies-arrayexpress
TranscriptomicsOncogenic SDH mutation underlies global epigenomic instability in gastrointestinal stromal tumor
We have discovered a striking connection between mitochondrial dysfunction and epigenomic instability, manifested by global biallelic DNA cytosine 5-methylation and loss of 5-hydroxymethycytosine within succinate dehydrogenase (SDH)-null gastrointestinal stromal tumors (GIST) relative to those beari...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-34387 | biostudies-arrayexpress
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