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UnknownIntegrated Analysis of the Mechanisms of Da-Chai-Hu Decoction in Type 2 Diabetes Mellitus by a Network Pharmacology Approach.
Not available
S-EPMC7204321 | biostudies-literature
TranscriptomicsTranscriptome profiling in 6-hydroxydopamine hemiparkinsonian rats reveals methamphetamine-mediated dopamine-independent changes in striatal gene expression.
Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle (MFB) is used extensively as a model of Parkinson’s disease. The present experiments examined whether a single injection of methamphetamine (METH) (2.5 mg/kg) could still influence striatal gene expression after 6-hydroxydop...
ORGANISM(S): Rattus norvegicus 
2010-09-21 | E-GEOD-24233 | biostudies-arrayexpress
MetabolomicsChanges in the Milk Metabolome of the Giant Panda (Ailuropoda melanoleuca) with Time after Birth – Three Phases in Early Lactation and Progressive Individual Differences
Ursids (bears) in general, and giant pandas in particular, are highly altricial at birth. The components of bear milks and their changes with time may be uniquely adapted to nourish relatively immature neonates, protect them from pathogens, and support the maturation of neonatal digestive physiology...
2015-03-31 | MTBLS165 | MetaboLights
ProteomicsA comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans
DNA damage causes genomic instability underlying many diseases, with traditional analytical approaches providing minimal insight into the spectrum of DNA lesions in vivo. Here we used untargeted chromatography-coupled tandem mass spectrometry-based adductomics (LC-MS/MS) to define the landscape of D...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2023-09-12 | PXD045311 | Pride
Adductomics Strp mrm 
ProteomicsProteomics of cassava storage roots before and after shoot pruning
Cassava (Manihot esculenta Crantz) is a food security crop for approximately 800 million people, primarily in developing economies. Cassava root yield is determined by the allocation of photoassimilated carbon within the plant, yet there is limited molecular and biochemical information about source-...
ORGANISM(S): Manihot esculenta (Cassava) (Jatropha manihot) 
2026-04-01 | PXD045690 | Pride
Manihot esculenta Storage roots Pruning Cassava 
ProteomicsStudy partners of NHS protein by proteomics
I am studying the NHS, the founding member of the NHS protein family, following the work of Yanan Wang, that discovered the WAVE shell complex, containing NHSL1 instead of WAVE (https://doi.org/10.1038/s41467-023-39276-w) Our recent experiments of the single cell migration show that NHS KO cells hav...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD070850 | Pride
ProteomicsPathology-driven epithelial sulfide loss reprograms the redox proteome and triggers Barrett’s esophagus
Background & AimsBarrett’s esophagus (BE), a metaplastic transformation driven by gastroesophageal reflux disease (GERD), induces oxidative stress but the underlying redox mechanisms remain poorly understood. Protein persulfidation (PSSH), a redox-sensitive, reversible, and antioxidative post-transl...
ORGANISM(S): Homo sapiens (Human) 
2026-06-02 | PXD047338 | Pride
Persulfidation  hydrogen sulfide  barrett’s esophagus  gastroesophageal reflux disease (gerd)  prostaglandin e2/interleukin 1/mtor cross-talk 
ProteomicsDiacetyl vapor exposure promotes ubiquitin proteasome stress and precedes bronchiolitis obliterans
Proteomic data from human airway epithelial cells treated with PBS and diacetyl vapor for two consecutive days. Samples were digested with trypsin, then analyzed by LC-MS/MS. Data was searched with MaxQuant.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-15 | MSV000086874 | MassIVE
ProteomicsComparative proteomic analysis of exosomes derived from endothelial cells and Schwann cells
Exosomes derived from endothelial cells and Schwann cells have been employed as novel treatments of neurological diseases, including peripheral neuropathy. Exosomal cargo plays a critical role in mediating recipient cell function. In this study, we thus performed a comprehensive proteomic analysis o...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-20 | PXD041547 | Pride
Proteomics Exosomes Endothelial cells Protein Schwann cells 
UnknownTranscription factor HNF4α2 promotes osteogenesis and prevents bone abnormalities in mice with renal osteodystrophy.
Not available
S-EPMC10231994 | biostudies-literature
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