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UnknownPlant Resistance to Fungal Pathogens: Bibliometric Analysis and Visualization.
Not available
S-EPMC9609943 | biostudies-literature
ProteomicsProteomics detection of mouse embryonic 17.5 dpc cultured ovaries in vitro
In this project, the ovaries of mice at 17.5 dpc embryonic stage were collected, and KN93, an inhibitor of CAMKII, and IWP2, an inhibitor of Wnt5a, were added for in vitro culture. Proteins affected by KN93 and IWP2, which were regulated by CAMKII and Wnt5a, were detected by proteomics technology, s...
ORGANISM(S): Mus Musculus 
2022-07-07 | PXD035136 |
TranscriptomicsmicroRNA profile of human liver tissues: hepatocellular carcinoma vs. matched noncancerous liver tissue
microRNA profiling of hepatocellular carcinoma vs. matched noncancerous liver tissue 166 pairs of hepatocellular carcinoma and matched noncancerous liver tissues
ORGANISM(S): Homo sapiens 
2011-08-15 | E-GEOD-31384 | biostudies-arrayexpress
TranscriptomicsExtensive promoter-centered chromatin interactions provide a topological basis for transcription regulation
Higher-order chromosomal organization for transcription regulation is poorly understood in eukaryotes. Using genome-wide Chromatin Interaction Analysis with Paired-End-Tag sequencing (ChIA-PET), we mapped long-range chromatin interactions associated with RNA polymerase II in human cells and uncovere...
ORGANISM(S): Homo sapiens 
2012-01-20 | E-GEOD-33664 | biostudies-arrayexpress
ProteomicsEZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Efforts to therapeutically target EZH2 have generally focused on inhibition of its methyltransferase activity, although it remains less clear whether this is the central mechanism whereby EZH2 promotes cancer. We demonstrate that EZH2 directly interacts with both MYC family oncoproteins, MYC and MYC...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029652 | Pride
Mycn Ap-ms Myc Ezh2 
ProteomicsTherapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability
Tumor cells must rewire nucleotide synthesis to satisfy the demands of unbridled proliferation. Meanwhile, they exhibit augmented reactive oxygen species (ROS) production which paradoxically damages DNA and free dNTPs. How these metabolic processes are integrated to fuel tumorigenesis remains to be ...
ORGANISM(S): Homo sapiens (Human) 
2023-12-27 | PXD043444 | Pride
Myc Plk1 Nudt1 Cancer，protac 
TranscriptomicsmRNA expression data from AG-haESC, E14 and MEF
Haploid cells are amenable for genetic analysis because they contain only one set of chromosomes.Here,we report the derivation of haESCs from androgenetic blastocysts. These cells, which we designated AG-haESCs, express classical ESC markers, are pluripotent, and contribute to various tissues includ...
ORGANISM(S): Mus musculus 
2012-04-26 | E-GEOD-35785 | biostudies-arrayexpress
GenomicsAscorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.
DNA demethylation occurs in multiple cellular processes but its regulation is poorly understood. Here we report that a vital nutrient factor ascorbic acid (AA), or vitamin C (Vc), induces DNA demethylation in mammalian cells. The levels of active 5mC oxidation products, 5-formylcytosine and 5-carbox...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-43262 | biostudies-arrayexpress
UnknownChromosome-level assembly and analysis of three hydroxy fatty acid-producing Physaria species.
Not available
S-EPMC12749981 | biostudies-literature
ProteomicsProteomic analysis of genes associated with mannitol metabolism in Saccharina
proteomic analysis of genes associated with mannitol metabolism in Saccharina explains the key role in mannitol metabolism and evolutionary significance of these genes
ORGANISM(S): Saccharina Japonica 
2018-04-28 | PXD009642 |
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