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To comprehensively elucidate the possible mechanism of short-term administration of emodin on the metabolic disturbance in vivo, our study utilized both LC/MS and NMR platforms for untargeted metabolomics studies. These analyses aimed to identify potential biomarkers associated with emodin-induced m...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD055000 | Pride
We treated a unicellular photosynthetic model cyanobacterium, Synechocystis sp. PCC 6803, with five different types of abiotic stresses including nitrogen starvation, iron deficiency, cold, heat, and darkness, and systematically identified proteins showing stress-induced differential expression and/...
ORGANISM(S): Synechocystis sp. PCC 6803 
2023-03-20 | PXD035771 | Pride
In this study, by using shotgun LC-MS/MS approach with the Tandem Mass Tag (TMTs) isobaric labelling technique we show that proteins in photosystem, inorganic carbon uptake and CO2 fixation systems are significantly changed in Δhik33 cells compared with WT cells.This is the normal culture condition ...
ORGANISM(S): Synechocystis sp. PCC 6803 
2017-05-19 | PXD005085 | Pride
Type 2 diabetes mellitus (T2DM) is an independent risk factor of Alzheimer's disease (AD), thus, identifying who among the increasing T2DM populations may develop into AD is important for early intervention. By using TMT-labeling coupled high-throughput mass spectrometry, we conducted a comprehensiv...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD027870 | Pride
Purpose: The goal of this study is to identify small non-conding RNAs which are involved in rice resistance to Xoo. Methods: Rice leaves were inoculated with the Xoo strain PXO61 at the four-leaf to five-leaf stage by the leaf-clipping method. Control rice plants were inoculated with water (mock ino...
ORGANISM(S): Oryza sativa Japonica Group 
By precisely dissected MS for proteomics, we found that donepezil remarkably restored (at high dose), even elevated (at low dose) the level of vacuolar protein sorting-associated protein 37D (VP37D), an autophagy-related protein, in hTauMS mice.
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD023297 | Pride
Here, we performed platelet proteomics in T2DM patients with MCI (T2DM-MCI) and without MCI (T2DM-nMCI)
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD023316 | Pride
Data from ProteomeXchange, PXD ID: PXD001246. File: GLY_M11_20140408.mzml. Published as part of Mol Cell Proteomics. 2014 Dec 13 . From the Abstract: {{i}} Large scale quantitative evaluation of the tightness of membrane association for non-transmembrane proteins is important for identifying true p...
ORGANISM(S): Synechococcus_phage_p60_uid14628, Synechococcus_phage_syn5_uid19763, Synechococcus_phage_syn9_uid17541, Synechococcus_phage_s_pm2_uid15223, Synechococcus_phage_s_rsm4_uid39923, Synechocystis_pcc_6803 
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