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Proteomics5-fluorouracil (5-Fu) resistant Bel/5Fu cell line and its parent Bel7402 cell line
The extensive drug resistance of hepatocellular carcinoma (HCC) has become the main cause of chemotherapy failure. The mechanisms leading to drug resistance in tumor cells are not well understood. Previous studies demonstrated that plasma membrane proteins play important roles in mediating drug disp...
ORGANISM(S): Homo Sapiens 
PXD015917 |
ProteomicsDifferent expressed proteins of HIV-infected long-term non-progress (LTNPs) and regular progressors (RPs)
To identify potential host factors promoting HIV-1 control and non-progressive infection, we employed mass spectrometry-based proteomic profiling to analyze three LTNPs and two PRs，in order to identify proteins expressed at higher levels in LTNPs.
ORGANISM(S): Homo Sapiens 
PXD050294 |
ProteomicsDifferent expressed proteins of HIV-infected long-term non-progressors (LTNPs) and regular progressors (RPs)
The whole blood samples were obtained from 3 LTNPs and 2 RPs HIV-1 infected patients, and the CD4+ T cells were isolated using anti-CD4-specific antibody-coated microbeads (130-045-101, Miltenyi Biotec, Germany) according to the manufacturer's instructions. Then the proteins extracted from the CD4+ ...
ORGANISM(S): Homo Sapiens 
PXD046078 |
ProteomicsDeep coverage proteome analysis of hair shaft for forensic individual identification
Hair shaft is one of the most common biological evidences found at crime scene. Due to the low amount and high degradation of nuclear DNA in hair shaft, it is difficult to achieve individual identification through routine method. The proteins in the hair shaft are stable and contain genetic polymorp...
ORGANISM(S): Homo Sapiens 
2022-06-22 | PXD034814 |
ProteomicsThe proteome and phosphorylproteome of human early erythropoiesis
In order to revealed the multiple protein functional modules and kinases networks of human early erythropoiesis. We isolated the CD34+ cells drived from Human umbilical cord blood samples and induced to undergo erythropoiesis in vitro. Then, the cultured erythroid cells were sorted with FACS and sam...
ORGANISM(S): Homo Sapiens 
2022-08-03 | PXD035785 |
MetabolomicsDeep functional analysis of synII, a 770 kb synthetic yeast chromosome
Here we report the design, construction and characterization of a 770 Kb synthetic yeast chromosome II (synII). With the UPLC-MS method, we demonstrated synII maintains a nearly wild-type phenotype and fitness despite hundreds of designer editing to it. Our phenomics, transcriptomics, proteomics dat...
2016-10-13 | MTBLS296 | MetaboLights
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