Sort   by:  
 Page size 
UnknownThe relationship between weight-adjusted-waist index, body mass index and diabetic retinopathy among American adults: a population-based analysis.
Not available
S-EPMC11470029 | biostudies-literature
ProteomicsStructural basis for the asymmetric binding of coactivator SRC1 to FXR-RXRα and allosteric communication within the complex
In this study, we employed an integrative approach to investigate the interaction between FXR-RXRα-DNA complex and the entire coactivator SRC1-NRID (nuclear receptor interaction domain). We constructed a multi-domain model of FXR-RXRα-DNA, highlighting the interface between FXR-DBD and LBD. Using HD...
ORGANISM(S): Homo Sapiens 
2025-02-08 | PXD060593 |
TranscriptomicsCGH analysis of AG-haESCs (androgenetic haploid embryonic stem cells)
The genomic DNA sample of AG-haESCs were compared to the C57BL/6J male mouse kidney by comparative genomic hybridization. The data confirmed that the haploid cells sustained genome integrity. The analysis was performed on a NimbleGen Mouse CGH 3x720K Whole-Genome Tiling Array to analyse the copy num...
ORGANISM(S): Mus musculus 
2012-04-26 | E-GEOD-35786 | biostudies-arrayexpress
TranscriptomicsmRNA expression data from AG-haESC, E14 and MEF
Haploid cells are amenable for genetic analysis because they contain only one set of chromosomes.Here,we report the derivation of haESCs from androgenetic blastocysts. These cells, which we designated AG-haESCs, express classical ESC markers, are pluripotent, and contribute to various tissues includ...
ORGANISM(S): Mus musculus 
2012-04-26 | E-GEOD-35785 | biostudies-arrayexpress
TranscriptomicsRBFox2 regulates a broad RNA program and is required for genome-wide targeting of polycomb complex
Increasing evidence suggests that diverse RNA binding proteins interact with regulatory RNAs to regulate transcription. RBFox2 is a ubiquitous RNA binding protein with prevalent expression in stem cells, heart, and brain. Here, we report a systematic dissection of the RBFox2-regulated RNA program in...
ORGANISM(S): Mus musculus 
2015-10-22 | E-GEOD-57926 | biostudies-arrayexpress
ModelsScott2026 - Dehalobacter syntrophic community metabolic model
Genome-resolved metagenomics and constraint-based metabolic modeling were used to define and analyze a 12-member anaerobic, Dehalobacter-containing mixed community enriched on chlorinated benzenes. The study examines pairwise ecological interactions, community-level cross-feeding, and minimal dechlo...
2026-09-02 | MODEL2605020001 | BioModels
UnknownNeck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Beijing Community Diabetes Study 23).
Not available
S-EPMC8097072 | biostudies-literature
ProteomicsATAD2 is a Potential Immunotherapy Target for Patients with Small Cell Lung Cancer Harboring HLA-A*0201
To identify the immune peptides in SCLC tumour cells that can be processed and presented by HLA-I, we performed LC–MS/MS analysis on 11 SCLC cell lines, representing the heterogeneity of SCLC subtypes. Ten of the cell lines were confirmed positive for HLA-I, and one was HLA-I-deficient. To analyse c...
ORGANISM(S): Homo Sapiens 
2024-11-26 | PXD058303 |
MetabolomicsVGLL4 modulates Paneth cells and sustains intestinal homeostasis.
Paneth cells are defensive cells in the intestinal tract, which secrete niche factors and antimicrobial peptides (AMPs) to maintain the small intestinal stem cell niche and immune homeostasis. Here, we show that Vestigial-like family member 4 (VGLL4) plays a pivotal role in maintaining small intesti...
2026-03-12 | MTBLS10456 | MetaboLights
ProteomicsGeneration of multi-disease spectral library
We created a multi-disease spectral library using 100 serum samples obtained from five patient groups, including healthy controls (n=20), Bechet's disease (n=20), non-small cell lung cancer (n=20) and liver diseases (n=20). The multi-disease spectral library included a total of 9,104 precursors and...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040603 |
Sort   by:  
 Page size