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MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
ProteomicsCombination of Metabolomics, Lipidomics and Molecular Biology to Investigation of Metabolic Disturbance of Short-Term Administration of Emodin
To comprehensively elucidate the possible mechanism of short-term administration of emodin on the metabolic disturbance in vivo, our study utilized both LC/MS and NMR platforms for untargeted metabolomics studies. These analyses aimed to identify potential biomarkers associated with emodin-induced m...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD055000 | Pride
Metabolomics Mouse Lc-ms Lipidomics 
TranscriptomicsPTIP-regulated genes in MEF
PPARg and C/EBPa cooperate to control preadipocyte differentiation (adipogenesis). However, the factors that regulate PPARg and C/EBPa expression during adipogenesis remain largely unclear. Here we show PTIP, a protein that associates with histone H3K4 methyltransferases, regulates PPARg and C/EBPa ...
ORGANISM(S): Mus musculus 
2009-05-29 | E-GEOD-16263 | biostudies-arrayexpress
GenomicsHistone H3K9 Methyltransferase G9a Represses PPAR? Expression and Adipogenesis [ChIP-Seq and RNA-Seq data]
PPAR? promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene...
ORGANISM(S): Mus musculus 
2013-02-01 | E-GEOD-41455 | biostudies-arrayexpress
TranscriptomicsHistone H3K9 Methyltransferase G9a Represses PPARγ Expression and Adipogenesis [Affymetrix expression data]
PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene...
ORGANISM(S): Mus musculus 
2013-02-01 | E-GEOD-41456 | biostudies-arrayexpress
UnknownKnowledge and attitudes among preschools staff in Shanghai, China, regarding epilepsy.
Not available
S-EPMC7550838 | biostudies-literature
UnknownCytokines Induce Monkey Neural Stem Cell Differentiation through Notch Signaling.
Not available
S-EPMC7244951 | biostudies-literature
UnknownEpigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway.
Not available
S-EPMC6921210 | biostudies-literature
TranscriptomicsH3K27 Methyltransferase PRC2 Represses Wnt Genes to Facilitate Adipogenesis
The Wnt/b-catenin signaling inhibits adipogenesis. Genome-wide profiling studies have revealed the enrichment of histone H3K27 methyltransferase PRC2 on Wnt genes. However, the functional significance of such a direct link between the two types of developmental regulators in mammalian cells, and the...
ORGANISM(S): Mus musculus 
2010-03-19 | E-GEOD-20054 | biostudies-arrayexpress
TranscriptomicsPCAF/GCN5-regulated genes in MEFs
Histone acetyltransferases (HATs) GCN5/PCAF and CBP/p300 are transcription coactivators. However, how these HATs regulate ligand-induced nuclear receptor target gene expression remains unclear. Here we show in mouse embryonic fibroblasts (MEFs), deletion of GCN5/PCAF specifically eliminates acetylat...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-20008 | biostudies-arrayexpress
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