So far, high-efficiency and high-throughput analysis of C-terminal peptides is still full of challenges. In order to make the chemical derivatization-based strategies more practical and efficient, in this study we developed a new method, named 2-pyridinecarboxaldehyde (2PCA) and biotin labeling bas...
Lung cancer in Chinese patients has distinct genomic features and lung squamous cell carcinoma (LUSC) has limited biomarkers for targeted therapy even though a lot of progress has been made in genomics research. Systematical research on LUSC at protein level will be beneficial to improve precision m...
Low cardiac output and kidney congestion are related to cardiac surgery-associated acute kidney injury (CSA-AKI), which is one of the most prevalent complications of cardiac surgery. This pathological process may be connected with a great risk of developing chronic kidney disease and mortality. This...
Acute kidney injury (AKI) associated with cardiac surgery may increase mortality and incidence rate of chronic kidney disease in critically ill patients. One purpose of this study was to investigate the possible correlations between urinary proteomic changes and cardiac surgery-related AKI.
