Sort   by:  
 Page size 
TranscriptomicsIdentification of avian RIG-I responsive genes during influenza infection
Transcriptional profiling of chicken embryonic fibroblasts (DF-1 cells) comparing the effects of chicken cells transfected with duck RIG-I compared to empty-vector transfected cells following with low or highly pathogenic avian influenza. Goal was to determine the effects of duck RIG-I on influenza-...
ORGANISM(S): Gallus gallus 
2012-12-12 | E-GEOD-29596 | biostudies-arrayexpress
ProteomicsCharacterizing metabolic drivers of Clostridioides difficile infection with activity-based hydrazine probes
Many enzymes require post-translational modifications or cofactor machinery for primary function. As these catalytically essential moieties are highly regulated, they act as dual sensors and chemical handles for context-dependent metabolic activity. Clostridioides difficile is a major nosocomial pat...
ORGANISM(S): Clostridioides difficile ATCC 43255 
2023-03-11 | PXD039143 | Pride
Metabolism C. difficile Cofactor Hydrazine Abpp 
MetabolomicsGNPS - Integrative multiomic analyses of dorsal root ganglia in diabetic neuropathic pain using proteomics, phosphoproteomics, and metabolomics
Diabetic peripheral neuropathy (DPN) is characterized by spontaneous pain in the extremities. Incidence of DPN continues to rise with the global diabetes epidemic. However, there remains a lack of safe, effective analgesics to control this chronic painful condition. Dorsal root ganglia (DRG) contain...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-09 | MSV000091027 | GNPS
ProteomicsIntegrative multiomic analyses of dorsal root ganglia in diabetic neuropathic pain using proteomics, phosphoproteomics, and metabolomics
Diabetic peripheral neuropathy (DPN) is characterized by spontaneous pain in the extremities. Incidence of DPN continues to rise with the global diabetes epidemic. However, there remains a lack of safe, effective analgesics to control this chronic painful condition. Dorsal root ganglia (DRG) contain...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-09 | MSV000091027 | MassIVE
GenomicThe Genetic Architecture of Smoking and Smoking Cessation

This study includes samples from two projects: Collaborative Genetic Study of Nicotine Dependence (COGEND; PI: Laura Bierut) and University of Wisconsin Transdisciplinary Tobacco Use Research Center (UW-TTURC; PI: Timothy Baker).

Data are available for an additional 1420 COGEND subjects th...

phs000404 | dbGaP
TranscriptomicsEbf2 is a selective marker of brown and beige adipogenic precursor cells (RNA-seq)
Brown adipocytes, muscle and dorsal dermis descend from precursor cells in the dermomyotome, but the factors that regulate commitment to the brown adipose lineage are unknown. Here, we prospectively isolated and determined the molecular profile of embryonic brown preadipose cells. Brown adipogenic p...
ORGANISM(S): Mus musculus 
2014-09-16 | E-GEOD-60441 | biostudies-arrayexpress
TranscriptomicsEbf2 is a selective marker of brown and beige adipogenic precursor cells (Microarray)
Brown adipocytes, muscle and dorsal dermis descend from precursor cells in the dermomyotome, but the factors that regulate commitment to the brown adipose lineage are unknown. Here, we prospectively isolated and determined the molecular profile of embryonic brown preadipose cells. Brown adipogenic p...
ORGANISM(S): Mus musculus 
2014-09-16 | E-GEOD-60442 | biostudies-arrayexpress
ProteomicsMolecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules
The production of secondary metabolites is one of the major mechanisms for beneficial rhizobacteria to antagonize plant pathogens. However, simultaneously producing large quantities of different secondary metabolites can pose great metabolic burdens and exerts a significant fitness cost on the produ...
ORGANISM(S): Pseudomonas Fluorescens F113 
2021-04-15 | PXD025403 |
TranscriptomicsTemporal patterns of gene expression in developing maize endosperm identified through transcriptome sequencing
Endosperm is a filial structure resulting from a second fertilization event in angiosperms. As an absorptive storage organ, endosperm plays an essential role in support of embryo development or seedling germination. The accumulation of carbohydrate and protein storage products in cereal endosperm pr...
ORGANISM(S): Zea mays 
2014-01-17 | E-GEOD-54131 | biostudies-arrayexpress
TranscriptomicsPemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma
We devised a high-throughput, cell-based assay to identify novel therapeutic compounds to treat Group3 medulloblastoma (G3 MB). Mouse G3 MBs, grown as neurospheres, were screened against a library of approximately 7,000 compounds including FDA-approved drugs. We identified two FDA-approved drugs, ...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-46406 | biostudies-arrayexpress
Sort   by:  
 Page size