Sort   by:  
 Page size 
ProteomicsDifferential Lysis Approach Enables Selective Extraction of Taxon-Specific Proteins for Gut Metaproteomics
A differential lysis approach was developed with different strength of lysis buffers (urea and/or sodium dodecyl sulfate) and applied on human stool samples to separate different microbial species to increase the depth of metaproteomic measurements. We showed that the lysates dominating by proteins ...
ORGANISM(S): Escherichia coli 
2023-03-27 | PXD016787 | Pride
Human Lc-msms Gut microbiome 
ProteomicsEstablishment of dimethyl labeling-based quantitative acetylproteomics in Arabidopsis
Protein acetylation, one of many types of post-translational modifications (PTMs), is involved in a variety of biological and cellular processes. In the present study, we applied both CsCl density gradient (CDG) centrifugation-based protein fractionation and a dimethyl-labelling-based 4C quantitativ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-03-14 | PXD006177 | Pride
Cscl density gradient (cdg) centrifugation Stable isotope dimethyl labelling Arabidopsis Squa-d Acetylproteomics 4c proteomic workflow Quantitative ptm proteomics 
UnknownGMrepo: a database of curated and consistently annotated human gut metagenomes.
Not available
S-EPMC6943048 | biostudies-literature
ProteomicsMultidimensional Molecular Characteristics of Early-Onset Endometrioid Endometrial Carcinoma, And Potential Predictors Of Response To Fertility Sparing Therapy
Endometrial carcinoma (EC) remains a public health concern with a growing incidence particularly in younger women. Women with early-onset endometrioid EC (EEEC) who wish to maintain fertility are a worldwide concern. To illuminate the molecular characteristics of EEEC, we undertook a large-scale mul...
ORGANISM(S): Homo sapiens (Human) 
2024-04-05 | PXD046507 | Pride
Endometrial carcinoma  early-onset  carcinogen signature  fertility-sparing treatment  siglec10 
ProteomicsPig novel protein from multiple tissues
We identified 24,431 protein isoforms encoded by 19,914 genes across 34 normal tissues using high-resolution mass spectrometry. This includes 7,693 protein isoforms corresponding to 5,875 genes which were firstly detected in current study.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2018-11-21 | PXD006991 | Pride
Multi-tissues Ls-mcmc Pig 
ProteomicsFunctional effects of sweeteners on ex vivo human gut microbiome
We systematically investigated the responses of five human gut microbiomes to 21 common sweeteners, using an approach combining high-throughput ex vivo microbiome culturing and metaproteomics to quantify functional changes in different taxa. Hierarchical clustering based on metaproteomic responses ...
ORGANISM(S): human gut metagenome 
2022-06-23 | PXD030458 | Pride
Artificial sweetener  microbiome  metaproteomics 
ProteomicsAn Isocaloric High-Fat Diet Improves Lifespan in Rats and Drosophila
The health effect of dietary fat has been one of the most vexing issues in the nutrition field. Few animal studies have examined the impact of high-fat diets on lifespan by controlling energy intake. In this study, we found that compared to a normal diet, an isocaloric high-fat diet (IHF) significan...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-01-06 | PXD022585 | Pride
Isocaloric High-fat diet Proteomics Lifespan 
ProteomicsSystematic Metaproteomic Mapping of Ex vivo Gut Microbiota Functional Responses to Therapeutic Drugs (1)
Some therapeutic compounds can influence our gut microbiota, but a comprehensive understanding of their impact on microbial systems ecology remains largely unexplored. This study examines the impact of 312 therapeutic compounds on metaproteomes of six ex vivo human gut microbiota, generating 4.6 mil...
ORGANISM(S): human gut metagenome 
2025-08-28 | PXD056888 | Pride
Gut microbiota Drug response Metaproteomic Lc-ms/ms 
ProteomicsSystematic Metaproteomic Mapping of Ex vivo Gut Microbiota Functional Responses to Therapeutic Drugs (3)
Some therapeutic compounds can influence our gut microbiota, but a comprehensive understanding of their impact on microbial systems ecology remains largely unexplored. This study examines the impact of 312 therapeutic compounds on metaproteomes of six ex vivo human gut microbiota, generating 4.6 mil...
ORGANISM(S): human gut metagenome 
2025-08-28 | PXD056968 | Pride
Gut microbiota Microbiome Drug response Functional redundancy Metaproteomics 
ProteomicsSystematic Metaproteomic Mapping of Ex vivo Gut Microbiota Functional Responses to Therapeutic Drugs (2)
Some therapeutic compounds can influence our gut microbiota, but a comprehensive understanding of their impact on microbial systems ecology remains largely unexplored. This study examines the impact of 312 therapeutic compounds on metaproteomes of six ex vivo human gut microbiota, generating 4.6 mil...
ORGANISM(S): human gut metagenome 
2025-08-28 | PXD056930 | Pride
Systems ecology Gut microbiome Metaproteomics Functional response 
Sort   by:  
 Page size