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The blood-brain barrier (BBB) is essential for central nervous system homeostasis, but most current in vitro models lack structural and functional fidelity. We developed a physiologically relevant human neurovascular unit microfluidic chip (hNVU-on-a-chip) incorporating brain microvascular endoth...

2025-10-28 | MTBLS13230 | MetaboLights
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
Gene expression profiling has provided critical insights into the molecular pathways underlying development of model organisms, however little information is available on regulated gene expression during human embryogenesis. We have now filled this important gap of knowledge by performing genome-wid...
ORGANISM(S): Homo sapiens 
Composition identification of spinach PEP complex by LC-MS/MS
ORGANISM(S): Spinacia Oleracea 
In order to understand the molecular mechanism underlying the action of dPCIF1 in early embryos, we carried out co-immunoprecipitation (co-IP) assays followed by mass spectroscopic analysis using dPCIF1GFP-KI early embryos (0.5–1.5 hours). In this assay, we identified a large number of dPCIF1-intera...
ORGANISM(S): Drosophila Melanogaster 
2024-01-18 | PXD048659 |
Schizophrenia has a high rate of misdiagnosis, leading to inappropriate or delayed treatment. Combining with extracellular vesicles’ (EVs) proteome profiling and XGBoost-based machine learning, we developed new pan-EVs markers and yielded personalized discrimination scores (PDS) for schizophrenia di...
ORGANISM(S): Homo Sapiens 
2023-02-20 | PXD040261 |
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