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Alzheimer’s disease (AD), the predominant cause of late-life dementia, has a multifactorial etiology. Since there are few therapeutic options for symptomatic AD, research is increasingly focused on the identification of pre-symptomatic biomarkers. Recently, evaluation of neuron-derived exosomal mark...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027561 | Pride
We generated an HK2 cell line overexpressing USAG-1 (referred to as USAG-1_OE), and extracted proteins for proteomic studies to identify differentially expressed proteins compared with the control cell line (referred to as CON).
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD066082 | Pride
Lactic acidosis and hypoxia are two prominent tumor microenvironmental stresses that are both known to exert important influences on gene expression and phenotypes of cancer cells. But very little is known about the cross-talk and interaction between these two stresses. We performed gene expression ...
ORGANISM(S): Homo sapiens 
Our integrative studies characterized SIRT3 as a delactylase to suppress HCC development, and the activation of SIRT3 might be a promising therapeutic mean for HCC.
ORGANISM(S): Homo Sapiens 
2023-01-03 | PXD039202 |
This project contains LC-MS/MS-based proteomic data generated from porcine serum samples. Protein identification and quantitative analyses were performed to characterize the serum proteome and investigate differential protein expression among experimental groups.
ORGANISM(S): Sus Scrofa Domesticus 
Proteomics in South China Agricultural University essentially refers to the study of protein characteristics at a large-scale level, including protein expression level, post-translational modification, protein-protein interaction and so on, so as to obtain an overall and comprehensive understanding ...
ORGANISM(S): Paguma Larvata 
2022-11-09 | PXD038083 |
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