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ProteomicsLC-MS/MS for harmaline-treated mice cerebellar cortex
Harmaline-induced tremor mice model has been well-recognized as a mature pharmacological model for ET, but his model has always been used to test drugs, the exact underlying mechanism of this mouse model has never been fully understood. This project is to provide a novel inspection for ET targeted t...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-05 | PXD055985 | Pride
Cerebellar cortex Harmaline Mice Lc-ms/ms 
ProteomicsImmunoprecipitates of KDM1A in HepG2 cells with stably overexpressed KDM1A
KDM1A requires an adaptor protein with specific DNA-binding activity to recognize chromatin sequence. We constructed HepG2 cells stably overexpressing KDM1A-Flag tag using lentivirus. We performed Co-IP with Flag-gel and we used LC-MS to determine the immunoprecipitates of KDM1A.
ORGANISM(S): Homo Sapiens 
2023-05-19 | PXD043284 |
Proteomicsproteome analyses reveal protein metabolism in Lactobacillus helveticus
Lactobacillus helveticus is a homofermentative lactic acid bacterium. It is widely used in the fabrication of Swiss cheese and other dairy products. The aim of this study was to elucidate the mechanism by which L. helveticus utilizes protein. L. helveticus CICC22171 were cultured in two different me...
ORGANISM(S): Uncultured Lactobacillus Sp. 
2021-05-11 | PXD025919 |
ProteomicsMetaproteomics characterizes human gut microbiota function in colorectal cancer
Alterations in gut microbiota have been implicated in the pathogenesis of Colorectal Cancer (CRC). Here we collected fecal samples from 14 CRC patients and 14 healthy volunteer cohorts, and characterized their microbiota using label-free quantitative metaproteomics method. We have quantified 30,062 ...
ORGANISM(S): Homo Sapiens 
2020-02-23 | PXD013386 |
ProteomicsIntegrative Proteomics and Phosphoproteomics Profiling Reveals Molecular Pathways in hypoxia adaptation of brain tissue in Lasiopodomys brandtii
Exposure to high-altitude hypoxic environments may lead to dysfunction in the central nervous system. Research on the hypoxic response mechanisms of hypoxia-tolerant animals can provide insights for animal conservation and the treatment of ischemic brain injury. In this study, we focused on Brandt's...
ORGANISM(S): Lasiopodomys Brandtii 
2024-10-17 | PXD056880 |
ProteomicsProteomic Screening of OLP/OLL-EVs
In this project, we first screened proteomics of OLP/OLL tissue-derived extracellular vesiclesEVs
ORGANISM(S): Homo Sapiens 
2021-06-25 | PXD026938 |
ProteomicsA Tissue-Specific Atlas of Mouse N-Glycoproteome
In this study, we employed StrucGP to generate the first high-resolution and site-specific N- glycoproteomic atlas across 24 diverse mouse tissues. This comprehensive dataset provides an unprecedented insight into the tissue-specific landscape of N-glycosylation, revealing how distinct glycan struct...
ORGANISM(S): Mus Musculus 
2025-05-07 | PXD063701 |
ProteomicsBartonella VBNC formation and resuscitation
DIA proteomic analysis of temp induced VBNC Bartonella henselae
ORGANISM(S): Bartonella Henselae Str. Houston-1 
2024-08-27 | PXD055316 |
ProteomicsLabel-free serum proteome in the rabbit CAS provocation model
A rabbit CAS provocation model was established to screen potential diagnostic biomarkers using quantitative serum proteomics
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-29 | PXD036383 |
ProteomicsMass spec results of Tmc7-GST pull-down
For the GST pull-down of DRG ganglion, the GST- or Tmc7-GST-associated beads were further incubated with cell lysates derived from DRG ganglion. The pulled-down proteins were then separated by SDS-PAGE gel electrophoresis and subsequently stained with silver staining Kit. Finally, the target molecul...
ORGANISM(S): Mus Musculus 
2024-03-08 | PXD050466 |
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