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ProteomicsMinimization of proteome reallocation explains metabolic shift in response to hierarchical utilization of mixed carbon sources
Protein expression levels were measured at different stages of the fermentation process
ORGANISM(S): Weizmannia coagulans DSM 1 = ATCC 7050 
2023-09-15 | PXD045169 | Pride
Metabolic shift Proteome allocation 
ProteomicsAKT/PACS2 participates in renal vascular hyperpermeability by regulating endothelial fatty acid oxidation in diabetic mice
HUVECs were purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA) and cultured in an Endothelial Cell Medium (Invitrogen, Carlsbad, CA, USA) containing 5% fetal bovine serum at 37°C in a 5% CO2 incubator. Cells were treated with 30 mM glucose and 0.1 mM palmitic acid (P0500, ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD033227 | Pride
Pacs2 Diabetes Endoplasmic reticulum Mitochondria Fatty acid oxidation Endothelial cell Vascular permeability 
ProteomicsSaccharomyces cerevisiae LC-MSMS
Multi-omics Elucidation of Resource Allocation for Enhanced Ethanol Production via Precise Glucose Control in Anaerobic Saccharomyces cerevisiae Fermentation
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-12-08 | PXD068901 | Pride
Saccharomyces cerevisiae lc-msms 
UnknownIntegrative Transcriptomic and Biochemical Analysis Reveals Key HSP20/Alpha-Crystallin Genes Associated with Heat Tolerance in Rice.
Not available
S-EPMC12279669 | biostudies-literature
UnknownSwimming exercise is a promising early intervention for autism-like behavior in Shank3 deletion rats.
Not available
S-EPMC9804047 | biostudies-literature
GenomicsHeterochromatin remodeling by CDK12 contributes to learning in Drosophila
We describe the epigenetic profiling of the H3K9me2 and HP1a in Drosophila third instar larvae before and after CDK12 depletion by RNA interference (RNAi). Here we show that CDK12 regulates heterochromatin dynamics in Drosophila chromosomes. Depletion of CDK12 induces the increased HP1a and H3K9me2 ...
ORGANISM(S): Drosophila melanogaster 
2015-11-02 | E-GEOD-63011 | biostudies-arrayexpress
Proteomicsquantitative proteomic analysis of phagocytes in oyster Crassostrea gigas
Invertebrates lack the adaptive immune system homologous to that of vertebrates, thus depend exceptionally on the innate immune system for the pathogen recognition and clearance. Phagocytes play a pivotal role in the innate immunity of invertebrates, but the molecular basis underlying their phagocyt...
ORGANISM(S): Crassostrea Gigas 
PXD009987 |
ProteomicsSpin-driven Enantioselective Regulation of Cyclooxygenase-2 Activity for Rheumatoid Arthritis Therapy via Chiral Gold Nanohelices
Electron-spin dynamics represent an unexplored dimension in enzymatic catalysis, where most regulatory strategies focus on modulating active-site chemistry. Here, we present a spintronic approach that employs chiral gold nanohelices (CAu) as electron spin polarizers to enantiospecifically modulate c...
ORGANISM(S): Mus Musculus 
PXD076742 |
ProteomicsPan-cancer and multi-omics analyses reveal the diagnostic and prognostic value of BAZ2B
The BAZ2B gene belongs to the bromodomain gene family. The proteins encoded by members of this gene family are important components of chromatin remodelling complexes and have a potential role in transcriptional activation. However, the biological significance of BAZ2B in pan-cancer is unknown. In t...
ORGANISM(S): Homo Sapiens 
PXD054319 |
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