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Biomimetic nanococrystals are prepared using the preferred combination of mitoxantrone and gambogic acid for rational drug delivery. The unique mechanism of obtained nanococrystals regulating pyroptosis genes through ribosomal stress is revealed by TMT-proteomics of 4T1 cells.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-27 | PXD053939 | Pride
We conducted proteomics analyses on three cocoons recovered from the Sapalli Tepe (approximately 2000 to 1500 BCE) site in Uzbekistan. This dataset contains LC-MS/MS data associated with the analysis of cocoons including Sapalli-C-1 (S1), Sapalli-C-2 (S2), Sapalli-C-3 (S3), Bombyx mori (S4), and Bom...
ORGANISM(S): Bombyx mori (Silk moth) 
2026-09-11 | PXD084037 | Pride
A septicemia model was established by intraperitoneal injection of lipopolysaccharide (LPS), followed by tail vein injection of imatinib in the treatment group and normal saline injection in the control group. Flow cytometry was used to detect inflammatory factors, and hematoxylin staining was used ...
ORGANISM(S): Mus Musculus 
2024-02-27 | PXD050204 |

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
The differences between wild-type mice and target gene knockout mice were analyzed by proteomic tests.
ORGANISM(S): Mus Musculus 
2025-01-13 | PXD059745 |
Proteomic analyses of the ocular posterior pole tissues at 6 weeks after induction of form-deprived myopia and lens-induced myopia models in guinea pigs.
ORGANISM(S): Cavia Porcellus 
2022-11-01 | PXD037872 |
Background: The role of viral infections as a mediator of systemic immune dysfunction leading to sepsis has received limited attention compared to the bacterial pathogens. The COVID-19 pandemic and the increased cases of sepsis in the absence of known bacterial pathogens have highlighted the clinica...
ORGANISM(S): Homo Sapiens 
2024-03-03 | PXD050303 |
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