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TranscriptomicsGenome-wide profiling of DNA methylation in two Arabidopsis ecotypes and their reciprocal hybrids - small RNA-seq
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
2011-12-22 | E-GEOD-34656 | biostudies-arrayexpress
ProteomicshiPSC-derived Mesendoderm cells LC-MSMS
NONO deficiency in hiPSCs results in a distinct defect in early cardiomyocyte differentiation. Mechanistically, NONO interacts with HOXA1 and regulates the dynamic expression of key genes during early cardiomyocyte differentiation. ChIP-seq analysis reveals that NONO loss reduces HOXA1 occupancy at ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-28 | PXD072401 | Pride
Lc-msms Mesendoderm Hipsc 
GenomicsGenome-wide profiling of DNA methylation in two Arabidopsis ecotypes and their reciprocal hybrids - Bisulfite-seq
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
2011-12-22 | E-GEOD-34657 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of DNA methylation in two Arabidopsis ecotypes and their reciprocal hybrids - mRNA-seq
Heterosis is a fundamental biological phenomenon characterized by the superior performance of a hybrid over its parents in many traits, but the underlying molecular basis remains elusive. To investigate whether DNA methylation plays a role in heterosis, we compared at single base-pair resolution th...
ORGANISM(S): Arabidopsis thaliana 
2011-12-22 | E-GEOD-34655 | biostudies-arrayexpress
TranscriptomicsCaste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior
Eusocial insects have evolved the capacity to generate adults with distinct morphological, reproductive and behavioural phenotypes from the same genome. Recent studies suggest that RNA editing might enhance the diversity of gene products at the post-transcriptional level, particularly to induce func...
ORGANISM(S): Acromyrmex echinatior 
2014-10-02 | E-GEOD-51576 | biostudies-arrayexpress
Genomicsena-DATASET-BGI-18-06-2015-05:57:10:511-19 - samples
We sequenced 205 patients who were suffering NSCLC with Exome sequencing method.
EGAD00001001398 | EGA
Genomicsena-DATASET-BGI-18-06-2015-04:55:13:301-17 - samples
We sequenced 292 patients who were suffering NSCLC with Whole genome sequencing or Exome sequencing method.
EGAD00001001397 | EGA
GenomicsFrequent alterations in cytoskeleton remodeling genes in primary and metastatic Chinese lung adenocarcinomas
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is largely uncharacterized. Here we present an integrated genomic and transcriptomic analysis of 335 primary lung adenocarcinomas and 35 corresponding lymph node metastases from Chinese patients. Altogether 13 si...
EGAS00001000982 | EGA
GenomicsBGI Data Access Committee
Data Access Committee EGAC00001000177
EGAC00001000177 | EGA
ProteomicsBispecific antigen therapy plasma proteome
Bispecific-antibody therapy (BAT), the next strategy of immunotherapy for tumor patients, has showed the enhanced antitumor benefits than the monotherapy. Yet, few effective biomarkers were developed to monitor the response. Here, we investigated the first BAT longitudinal plasma proteome profiling ...
ORGANISM(S): Homo Sapiens 
2024-02-20 | PXD039260 |
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