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UnknownMicrobiome-Metabolome Reveals the Contribution of the Gut-Testis Axis to Sperm Motility in Sheep (Ovis aries).
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S-EPMC10044597 | biostudies-literature
ProteomicsThe parallel reaction monitoring (PRM) target sequencing based on the comparative proteomic profiling in sheep spermatozoa under non-capacitating (NC) and capacitating (CAP) conditions in vitro using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) combined with tandem mass tag (TMT) labeling strategy
To verify protein expression levels obtained by TMT LC-MS/MS analysis strategy, the expression levels of differentially abundant proteins in NC and CAP groups were selected and quantified by a PRM assay.
ORGANISM(S): Bos taurus (Bovine) 
2022-07-14 | PXD034330 | Pride
Spermatozoa Prm Tmt Proteomic Lc-ms/ms Capacitation 
ProteomicsProteomic Analysis of Human Nucleus Pulposus in Young and Elderly Individuals Using TMT Quantification
This project investigates the differential proteomic profiles of human nucleus pulposus samples from young and elderly individuals. Using Tandem Mass Tag (TMT) quantification, we aim to identify and compare protein expression differences between the two groups. The research explores the biological i...
ORGANISM(S): Homo Sapiens 
2025-06-23 | PXD065307 |
ProteomicsPeptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage
Hypoxic-ischemic brain injury (HIBD) causes neonatal death and serious neurological disability; however, there are currently no promising therapies for it excepting cooling. Therefore, in this study, we used peptidome analysis to identify differentially expressed peptides in cerebrospinal fluid (CS...
ORGANISM(S): Homo Sapiens 
2020-03-01 | PXD017797 |
ProteomicsDIA-based raw mass spectrometry proteomics data of oviduct in goat
DIA-based LC-MS/MS method was used to obtain follicular and luteal phase proteomics data from the oviducts of high- and low-fertility goats, and to mine the oviducts for biomarkers that regulate fertility in goats through bioinformatics analysis of differential proteins.
ORGANISM(S): Capra Hircus 
2022-11-13 | PXD038122 |
ProteomicsPD-L1 Mediated Immune Evasion in Triple Negative Breast Cancer Is Linked to the Loss of ZNF652
The intrinsic regulation of PD-L1 expression remains unclear. Here we report that ZNF652 is a potent transcription repressor of PD-L1. ZNF652 frequently loses heterozygosity (LOH) in various cancers. Higher LOH rate and lack of estrogen-inducible transcription lead to suppressed expression of ZNF652...
ORGANISM(S): Homo Sapiens 
2023-09-29 | PXD045945 |
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