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ProteomicsCoordinated regulation of transcription by CcpA and the Staphylococcus aureus two component system HptRS
Total cytosolic protein fractions of Staphylococcus aureus strains SA564, SA564-ΔhptRS, SA564-ΔccpA and SA564-ΔhptRS/ccpA were analyzed by LC-MSE . Five biological replicates of each strain, cultivated in TSB and TSB-dex, during the exponential (2h) and post exponential (6h) growth phases (80 sampl...
ORGANISM(S): Staphylococcus aureus 
2018-12-19 | PXD008708 | Pride
Postexponential growth phase Hpts Ccpa Hptr Glucose Exponential growth phase Carbon catabolite Hptrs Staphylococcus aureus 
MetabolomicsMulti-omics resources for targeted agronomic improvement of pigmented rice

Pigmented rice (Oryza sativa L.) is a rich source of nutrients, but pigmented lines typically have long life cycles and limited productivity. Here we generated genome assemblies of 5 pigmented rice varieties and evaluated the genetic variation among 51 pigmented rice varieties by reseque...

2023-03-27 | MTBLS3320 | MetaboLights
UnknownProximate drivers of spatial segregation in non-breeding albatrosses.
Not available
S-EPMC4956756 | biostudies-literature
TranscriptomicsTranscription profiling of mouse uterus exposed to DES reveals altered uterine gene expression that maybe associated with neoplasia later in life
Previously, we described a mouse model where the well-known reproductive carcinogen, diethylstilbestrol (DES), caused uterine adenocarcinoma following neonatal treatment. Tumor incidence was dose-dependent reaching >90% by 18 mo. following 1000 µg/kg/day of DES. These tumors followed the initiation...
ORGANISM(S): Mus musculus 
2008-11-06 | E-GEOD-5825 | biostudies-arrayexpress
ProteomicsProteomic and phosphoproteomic profiling of SFTPCI73T expressing patient-specific pluripotent stem cell-derived alveolar epithelial type 2 cells and their gene-edited corrected counterparts.
We performed proteomic and phosphoproteomic profiling of cells derived from human induced pluripotent stem cells (iPSCs) using our previously described distal lung directed differentiation protocol to generate alveolar epithelial type 2 cells (iAEC2s). We used the SPC2 human iPSC line and specifical...
ORGANISM(S): Homo sapiens (Human) 
2021-10-07 | PXD022334 | Pride
Autophagy Proteomics Pluripotent stem cells Pulmonary fibrosis Alveolar epithelial type 2 cells 
ProteomicsComprehensive Molecular Analysis of Tissue from Epileptic Patients Indicates Disruption of Energy, Redox and Purine Metabolism in Seizure Onset Comprehensive Molecular Analysis of Tissue from Epileptic Patients Indicates Disruption of Energy, Redox and Purine Metabolism in Seizure Onset
Epilepsy is a disorder that affects around 1% of the population. Epilepsy is widely controlled by anti-convulsant drugs; however, approximately one third of patients do not respond to this treatment. In many cases of drug resistant epilepsy (DRE) surgical removal of the indicated tissue may be per...
ORGANISM(S): Homo sapiens (Human) 
2022-03-07 | PXD010415 | Pride
Human  brain  lc-ms/ms  mse 
ProteomicsA systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S)
We longitudinally profiled plasma proteomes in 54 adults vaccinated with the BNT162b2 (Pfizer-BioNTech) or ChAdOx1-S (Oxford-AstraZeneca) vaccines. Blood was collected pre-vaccination (V0) and 1-7 days after the 1st doses (BNT162b2 or mRNA-1273, V1) to assess innate and early adaptive responses. We ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-01 | PXD036608 | Pride
Sars-cov-2 Proteomics Plasma Vaccination Covid-19 vaccine 
UnknownDiabetes autoantibodies do not predict progression to diabetes in adults: the Diabetes Prevention Program.
Not available
S-EPMC4138247 | biostudies-literature
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
Not available
S-EPMC8362594 | biostudies-literature
UnknownSociodemographic, Clinical, and Psychosocial Predictors of Short- and Long-term Study Retention in the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS).
Not available
S-EPMC12451849 | biostudies-literature
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