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MetabolomicsUHPLC-Q-TOF MS-Based Serum Metabolomics Reveals the Therapeutic Effects of Berberine and Wumei Wan on APCmin/+ Mice

APCmin/+ mice (8-week-old) and wild-type C57BL/6 controls were divided into MOD (saline), BBR (100 mg/kg berberine), WMW (17 g/kg Wu Mei Wan), and CON (saline) groups. All mice received daily gavage for 10 weeks under a 60% high-fat diet. Serum samples were collected after euthanasia and subjecte...

2025-10-16 | MTBLS12598 | MetaboLights
MetabolomicsMetabolomic insights into the phytochemical profiles and seasonal shifts of Fucus serratus and F. vesiculosus harvested in Danish coastal waters (Aarhus Bay) – an untargeted high-resolution mass-spectrometry approach

This study investigated the year-round metabolomic variation in Fucus serratus (FS) and F. vesiculosus (FV) collected monthly from Danish costal water around Aarhus Bay. Untargeted high-resolution liquid chromatography-mass spectrometry profiling (LC-HRMS), combined with multivariate data analysi...

2025-10-23 | MTBLS13204 | MetaboLights
MetabolomicsEffects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics
Major depressive disorder (MDD), also known as depression, is a state characterized by low mood and aversion to activity. Platycodins Folium (PF) is the dried leaf of Platycodon grandiflorum, with anti-inflammatory and antioxidative activities. Our previous research suggested that PF was rich in fla...
2020-06-03 | MTBLS952 | MetaboLights
ProteomicsOn the characterisation of the porcine gland-specific salivary proteome using MALDI-TOF/TOF MS and Q-Exactive orbitrap MS/MS
To expand the knowledge on the porcine salivary proteome, secretions from the three major salivary glands were collected from anaesthetised piglets. Pilocarpine and isoproterenol were simultaneously injected intraperitoneally to increase the volume and protein concentration of the saliva, respective...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-02-15 | PXD008853 | Pride
Salivary proteome Lc-ms Itraq Gland-specific saliva Pig 
MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
ProteomicsTowards a better understanding the testicular proteome of domestic pig
For gaining additional insights into the composition of the testicular proteome of the domestic pig (Sus scrofa domestica), we conducted 2DE-MS. Two-dimensional SDS PAGE was run on testicular lysates of three boars, with three gels per boar. Upon matching across gels, we arbitrarily selected protein...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-08-12 | PXD015649 | Pride
Proteomics Sus srofa 2de-ms 
UnknownDataset on LC-Q-TOF/MS tentative identification of phytochemicals in the extract of Vernonia amygdalina leaf through positive ionization.
Not available
S-EPMC6249520 | biostudies-literature
ProteomicsPytheas E. coli 16S rRNA sample analysis
Mass spectrometry remains an important method for analysis of modified nucleosides ubiquitously present in cellular RNAs, in particular for ribosomal and transfer RNAs that play crucial roles in mRNA translation and decoding. Furthermore, modifications have effect on the lifetimes of nucleic acids i...
ORGANISM(S): Escherichia coli 
2022-05-04 | PXD030538 | Pride
16s Rna Ribosome Isotope labeling Pytheas 
MetabolomicsBacterial profiles analysed by REIMS using Xevo G2-XS

Rapid evaporative ionisation mass spectrometry (REIMS) has been demonstrated capable of bacterial speciation by differentiation of their metabolic/lipidomic profiles. Previous work has shown the use of hand-held probes [1,2], and this dataset makes use of a robotic sampling probe which allows for...

2025-07-11 | MTBLS11776 | MetaboLights
MetabolomicsCoordinate Regulation of Metabolite Glycosylation and Stress Hormone Biosynthesis by TT8 in Arabidopsis
Secondary metabolites play a key role in coordinating ecology and defense strategies of plants. Diversity of these metabolites arise by conjugation of core structures with diverse chemical moieties, such as sugars in glycosylation. Active pools of phytohormones, including those involved in plant str...
2016-10-03 | MTBLS129 | MetaboLights
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