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MetabolomicsDirect infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control
Direct-infusion mass spectrometry (DIMS) metabolomics is an important approach for characterising molecular responses of organisms to disease, drugs and the environment. Increasingly large-scale metabolomics studies are being conducted, necessitating improvements in both bioanalytical and computatio...
2022-05-16 | MTBLS79 | MetaboLights
ProteomicsIdentification of DENR-interacting proteins in NIH3t3 cells using a co-IP MS-MS approach on endogenously tagged DENR.
Among the transcript features that regulate translation rate, upstream open reading frames (uORFs) have emerged as a major class of inhibitory elements which limit how many scanning ribosomes reach the start codon of the main protein coding sequence (CDS). Two processes are implicated in ensuring th...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-01 | PXD051482 | Pride
Co-immunoprecipitation Denr Translation Mcts2 Mcts1 Re-initiation 
TranscriptomicsAstrocytes’ response to Flunarizine combined with irradiation
Bulk RNAseq analysis of mRNA content of human primary astrocytes irradiated with 10 Gy and/or treated with Flunarizine 10uM.
ORGANISM(S): Homo sapiens 
2025-08-19 | E-MTAB-15215 | biostudies-arrayexpress
UnknownThe orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA.
Not available
S-EPMC3326314 | biostudies-literature
TranscriptomicsHaematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cells (Bulk RNA-SEQ Mouse)
Clonal haematopoiesis (CH), the expansion of blood-cell clones carrying acquired mutations, is an independent risk factor for cardiovascular disease. Although mutations in DNMT3A and TET2 are well studied, the cardiovascular consequences of KDM6A mutations remain unclear. KDM6A is an X-linked histon...
ORGANISM(S): Mus musculus 
2026-08-24 | E-MTAB-17560 | biostudies-arrayexpress
UnknownNoninferior Immunogenicity and Consistent Safety of Respiratory Syncytial Virus Prefusion F Protein Vaccine in Adults 50-59 Years Compared to ≥60 Years of Age.
Not available
S-EPMC11478578 | biostudies-literature
GenomicsDATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
DATA_SET_ICGC_PedBrainTumor_Medulloblastoma
EGAD00001000122 | EGA
TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
UnknownPostoperative Staphylococcus aureus Infections in Patients With and Without Preoperative Colonization.
Not available
S-EPMC10618839 | biostudies-literature
UnknownRelationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Not available
S-EPMC11658795 | biostudies-literature
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