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ProteomicsCaspase-3 cleaves extracellular vesicle proteins during auditory brainstem development
Sound localization requires extremely precise development of auditory brainstem circuits, the molecular mechanisms of which are largely unknown. We previously demonstrated a novel requirement for non-apoptotic activity of the protease caspase-3 in chick auditory brainstem development. Here, we used ...
ORGANISM(S): Gallus gallus (Chicken) 
2020-10-16 | PXD021728 | Pride
Neurodevelopment Chicken Brainstem Caspase-3 
ProteomicsApoptotic auditory brainstem of E13 chick embryo
We characterized the proteome of the auditory brainstem of a chick embryo on embryonic day 13, when apoptosis occurs in auditory nuclei. We identified caspase substrates by searching the peptidome for peptides C-terminal to caspase-typical cleavage sites.
ORGANISM(S): Gallus gallus (Chicken) 
2022-04-01 | PXD030697 | Pride
Auditory Chick Caspase Brainstem Apoptosis 
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