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ProteomicsEffect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome
The exact molecular mechanisms by which PTGFRN influences cancer progression are still unknown. Our laboratory set out to investigate how PTGFRN knockdown affected the expression of other proteins. We also carried out co-immunoprecipitation experiments using a monoclonal anti-PTGFRN antibody. We emp...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048092 | Pride
A431 Ptgfrn Mass spectrometry Interactome Proteome Co-immunoprecipitate 
ProteomicsTenotomized Achilles tendons of MRL/MpJ mice show scar-mediated healing, but have superior recovery of biomechanical properties
The purpose of this project is to determine changes in proteins and signaling pathways in injured tendons of C57BL/6j and MRL/MpJ mice. The MRL.MpJ mice have been reported to have a strong repair ability compared to that of C57BL/6j mice. Identifying signaling pathways in MRL/MpJ tendons that are di...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-16 | PXD057712 | Pride
Tendon c57bl/6j Injury Mrl/mpj Achilles tendon 
ProteomicsInflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles
Polymeric nanoparticles (NPs) have emerged as promising tools for immunomodulation in various disease contexts. The interactions between the NP surface and plasma-resident biomolecules result in the formation of a biomolecular corona (BC), which varies patient-to-patient and as a function of disease...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-17 | PXD050918 | Pride
Biomolecular corona Inflammation Immunomodulation Nanoparticles Immunogenicity 
ProteomicsDisruption of Heme Uptake and PrrF sRNA Expression in the Pseudomonas aeruginosa PhuS H209A Variant Induces a Metabolic Stress-Response
The Pseudomonas aeruginosa heme-binding protein PhuS plays a central role in coordinating heme utilization with iron homeostasis through the PrrF small RNAs. Proteomic and metabolomic analyses of the phuSH209A allelic strain demonstrated that the previously characterized in vitro disruption of PhuS ...
ORGANISM(S): Pseudomonas aeruginosa PA103 
2026-09-28 | PXD079786 | Pride
Heme-binding protein Pseudomonas aeruginosa Prrf small rnas Phus H209a variant 
ProteomicsMining Missing Protein Landscape in Subcellular Proteome of Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) have capacity of self-renewal and multi-lineage differentiation into derivatives of three germ layers that are of clinical importance for regeneration medicine. Despite the significant progress of hESCs study for clinical application, factors responsible for mainta...
ORGANISM(S): Homo Sapiens (human) 
PXD009840 | JPOST Repository
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