Sort   by:  
 Page size 
ProteomicsThermal proteome profilling of Ergothionine treated-cells reveals its binding to cystathionine-gamma-lyase (CSE)
Ergothioneine (ET), a dietary thione/thiol, is receiving growing attention for its possible benefits in healthy aging and metabolic resilience. Our study investigates ET's effects on healthspan in aged animals, revealing extension of lifespan and enhanced mobility in Caenorhabditis elegans, accompan...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-20 | PXD051609 | Pride
Ergothioneine Healthspan Persulfidation Hydrogen sulfide Nad 
ProteomicsSgt1 interactome analysis under proteostatic stress and steady state conditions
Buildup of misfolded proteins are prevented by chaperone-assisted refolding and/or proteasome dependent degradation. The coordination of these two protein quality control (PQC) systems is not fully understood. We identified the essential Hsp90 co-chaperone Sgt1 as a new member of a general PQC linki...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-07-02 | PXD016174 | Pride
Heat shock Sgt1 Hapi Saccharomyces cerevisiae Protein quality control 
ProteomicsA new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress
Biological membranes have a stunning ability to adapt their composition in response to physiological stress and metabolic challenges. Little is known how such perturbations affect individual organelles in eukaryotic cells. Pioneering work provided insights into the subcellular distribution of lipids...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-03-05 | PXD048553 | Pride
Organelle isolation Proteomics Upr Lipid bilayer stress Lipidomics Membrane 
UnknownMethotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
Not available
S-EPMC4486345 | biostudies-literature
TranscriptomicsTranscription profiling of mouse Cannabinoid receptor double knockouts (Cnr1 -/- /Cnr2 -/-) in CHS model to investigate cutaneous contact hypersensitivity
We evaluated cutaneous contact hypersensitivity (CHS) in Cnr1-/-/Cnr2-/- animals using the obligate contact allergen 2,4-dinitrofluorobenzene (DNFB), which generates a specific cutaneous T-cell mediated allergic response upon repeated allergen contact. Allergic contact dermatitis affects about 5% of...
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-7694 | biostudies-arrayexpress
ProteomicsIdentification of protein-trichloroethene interactions during organohalide respiration revealed by thermal proteome profiling
The organohalide-respiring Sulfurospirillum multivorans uses chlorinated ethenes as electron acceptors for growth under anoxic conditions. However, little is known about the interaction of these substrates with proteins. Here, we apply thermal proteome profiling (TPP) to analyze enzyme-trichloroethe...
ORGANISM(S): Sulfurospirillum multivorans DSM 12446 
2018-06-06 | PXD009308 | Pride
Thermal proteome profiling (tpp)  interaction proteome  organohalide respiration  reductive dehalogenases  sulfurospirillum multivorans  dehalococcoides mccartyi  quantitative proteomics 
UnknownGenome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.
Not available
S-EPMC6345037 | biostudies-literature
UnknownRivaroxaban vs Vitamin K Antagonist in Patients With Atrial Fibrillation and Advanced Chronic Kidney Disease.
Not available
S-EPMC11198259 | biostudies-literature
Unknown[Pandemic-related sales ban of fireworks in Germany leads to a significant reduction of firework-related eye injuries].
Not available
S-EPMC9713168 | biostudies-literature
UnknownMachine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score.
Not available
S-EPMC8344569 | biostudies-literature
Sort   by:  
 Page size