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Alzheimer's disease (AD) is a devastating neurodegenerative disorder that threatens to reach epidemic proportions as our population ages. Although much research has examined molecular pathways associated with AD, relatively few studies have focused on critical early stages. Our prior microarray stud...
ORGANISM(S): Homo sapiens 
Shellfish allergy is a major global health concern, with prawns being among the most common elicitors of allergic reactions. This project describes a comparative allergenomic analysis of the most widely consumed prawn species worldwide: black tiger prawn (Penaeus monodon) and white leg prawn (Litop...
ORGANISM(S): Penaeus 
2026-09-07 | PXD072307 | Pride
This study explored the proteomic basis of cold adaptation, quantifying 11,394 proteins across 6 metabolic tissues and plasma. Systems level analysis revealed an enrichment for proteins involved in metabolism. In brown adipose tissue (BAT), cold adaptation was associated with enhanced glucose utilis...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-22 | PXD055965 | Pride
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
The two major mammalian adipose tissue depots are subcutaneous adipose tissue (SAT), which is associated with metabolic protection, and abdominal/visceral (VAT), which contributes to metabolic disease. To investigate the molecular underpinnings of these differences, we conducted a comprehensive anal...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-13 | PXD039523 | Pride
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