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UnknownMucin is produced by clara cells in the proximal airways of antigen-challenged mice.
Not available
S-EPMC10862391 | biostudies-literature
TranscriptomicsInterplay between AP-1 and ERalpha in regulating gene expression and proliferation networks in breast cancer cells
Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription factor that plays an important role in breast cancer. Estrogen-dependent gene regulation by ERalpha can be mediated by interaction with other DNA-binding proteins, such as activator protein-1 (AP-1). The nature of such interaction...
ORGANISM(S): Homo sapiens 
2012-08-05 | E-GEOD-36586 | biostudies-arrayexpress
TranscriptomicsHNF1-alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP1 & ChREBP activation
Biallelic inactivating mutations of the transcription factor 1 gene (TCF1), encoding hepatocyte nuclear factor 1a (HNF1a), were identified in 50% of hepatocellular adenomas (HCA) phenotypically characterized by a striking steatosis. To understand the molecular basis of this aberrant lipid storage, w...
ORGANISM(S): Homo sapiens 
2007-05-01 | E-GEOD-7473 | biostudies-arrayexpress
ProteomicsTriple Null, a soybean bred to lack major seed allergen P34 and bioactive lectin and kunitz trypsin inhibitor
Seeds, including soybean (Glycine max), contain bioactive proteins with anti-nutritional and immunological properties that affect metabolism and assimilation of seed derived nutrients and as allergens that can induce escalating adverse immune responses. The presence of anti-nutritional proteins requ...
ORGANISM(S): Glycine max 
2022-02-23 | PXD000967 | Pride
Null Seed Soybean Allergen 
TranscriptomicsRole of Serine 134 phosphorylation of the glucocorticoid receptor (GR) in glucocorticoid signaling
In response to environmental stressors and a variety of inflammatory cytokines, p38 MAPKs become directly activated. Here we report the human glucocorticoid receptor (GR) Serine 134 as a novel target for p38 MAPK. Unlike most other phosphorylation events that occur on the GR, phosphorylation of Ser1...
ORGANISM(S): Homo sapiens 
2011-10-04 | E-GEOD-28912 | biostudies-arrayexpress
TranscriptomicsTranscriptomic responses of HepG2/C3 and A549 cells to the organophosphate flame retandant TDCIPP
Human cell cultures A549 and HepG2/C3 were exposed to 0-100 micromolar Tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) in 0.5% DMSO or to 0.5% DMSO alone for 24 h. RNA was prepared and labeled with Cy3. Agilent SurePrint G3 Human GE v2 8x60k Microarrays, Agilent design ID 039494, were used to profile ...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-MTAB-3323 | biostudies-arrayexpress
UnknownAlternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.
Not available
S-EPMC1769375 | biostudies-literature
UnknownA chromosome-scale genome assembly and evaluation of mtDNA variation in the willow leaf beetle Chrysomela aeneicollis.
Not available
S-EPMC10320752 | biostudies-literature
UnknownEmerging investigator series: characterization of silver and silver nanoparticle interactions with zinc finger peptides.
Not available
S-EPMC6746224 | biostudies-literature
TranscriptomicsTranscription profiling of C. elegans late larvae and adult developmental stages treated with low-intensity microwave irradiation reveals no substantial alteration in gene expression
Reports that low-intensity microwave radiation can induce heat-shock reporter gene expression in the nematode, Caenorhabditis elegans, have recently been reinterpreted as a subtle thermal effect caused by very slight heating. This study used a microwave exposure system (1.0 GHz, 0.5 W power input; ...
ORGANISM(S): Caenorhabditis elegans 
2009-03-20 | E-GEOD-10787 | biostudies-arrayexpress
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