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TranscriptomicsWhole-genome microarray analysis of primary, secondary, tertiary and quaternary memory CD8 T cells
The transcriptome of naive OT-I T cells was compared to memory CD8 T cells after 1, 2, 3, or 4 infection with ovalbumin expressing Listeria monocytogenes (LM-OVA). Naive Thy1.1 OT-I T cells were adoptively transferred into Thy1.2 naive hosts prior to infection with LM-OVA. The resulting memory CD8 T...
ORGANISM(S): Mus musculus 
2010-07-09 | E-GEOD-21360 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lymphomagenesis induced by conditional expression of transgenic c-Myc oncogene in six different tumor cell lines
Lymphomagenesis was induced by conditional expression of transgenic c-Myc oncogene. Profile of genes expressed in tumor cells was compared with profile of genes in the same cell line treated for 12 hours with doxycycline to abrogate expression of transgenic c-Myc. Six different tumor cell lines wer...
ORGANISM(S): Mus musculus 
2004-09-17 | E-MEXP-169 | biostudies-arrayexpress
TranscriptomicsExpression data of cHL cell lines after KLF4 activation
Characteristic extinguishing of B-cell phenotype in cHL is believed to be a result of transcription factor network deregulation due to the overexpression of repressor proteins ID2 and ABF-1. KLF4 is a versatile transcription factor, participating in regulation of differentiation processes in various...
ORGANISM(S): Homo sapiens 
2010-10-22 | E-GEOD-21296 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of the pancreas samples from animals showing autoimmune pancreatitis and chronic pancreatitis
Autoimmune pancreatitis (AIP) is a disease with unclear immunologic triggers. This study shows that the pancreatic stellate cells are involved in the regulation of the immune response and can cause autoimmunity when the NF-κB signalling in these cells is disrupted.
ORGANISM(S): Mus musculus 
2022-03-31 | E-MTAB-7274 | biostudies-arrayexpress
Transcriptomicsmurine MYC-dependent lymphoma cells: Dox vs. NoDox treatment
miRNA expression profiling of murine MYC-dependent lymphoma cell lines harboring the MYC-transgene in a Tet-off system comparing control untreated lymphoma cells (high MYC expression state) with 18hours Dox treated lymphoma cells (low MYC expression state). Keywords: inducible expression system Two...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-12394 | biostudies-arrayexpress
TranscriptomicsExpression of constitutively active FOXO3 in murine forebrain leads to a loss of neural progenitors
We have generated transgenic mice with tetracycline-regulated conditional expression of a constitutively active allele of FoxO3 under the control of the forebrain-specific CaMKIIa promoter. In adult animals, there was a reduction of brain weight by 30% and an almost complete loss of the dorsal denta...
ORGANISM(S): Mus musculus 
2012-09-13 | E-GEOD-21089 | biostudies-arrayexpress
UnknownOncolytic viruses expressing MATEs facilitate target-independent T-cell activation in tumors
Not available
S-SCDT-10_1038-S44321-024-00187-Y | biostudies-other
UnknownSpontaneous cervical artery dissection is associated with a distinct peripheral immune cell signature.
Not available
S-EPMC12826460 | biostudies-literature
TranscriptomicsGene expression data from murine heart ventricles E12.5 with and without cardiomyocyte-specific expression of constitutively active IKK2
The transcription factor NF-κB has been associated with a range of pathological conditions of the heart, mainly based on its function as a master regulator of inflammation and pro-survival factor. Here, we addressed the question what effects activation of NF-κB can have during murine heart developme...
ORGANISM(S): Mus musculus 
2015-10-14 | E-MTAB-3971 | biostudies-arrayexpress
UnknownILROG emergency guidelines for radiation therapy of hematological malignancies during the COVID-19 pandemic.
Not available
S-EPMC7243146 | biostudies-literature
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