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Clericuzio-type poikiloderma with neutropenia (PN, Mendelian Inheritance in Man (MIM) accession 604173) is a rare genodermatosis associated to mutations in the MPN1 gene. The aim of this experiment was to investigate the the effect of MPN1 mutations on pre-mRNA transcripts maturation. We compared th...
ORGANISM(S): Homo sapiens 
miRNAs are short regulatory single stranded RNA sequences that upon complementary binding to mRNAs lead to the inhibition or degradation of their targets. This regulatory mechanisms has been shown to play crucial roles throughout the whole life cycle of animals and plants as well as in disease. Whil...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-31 | PXD014484 | Pride
HEK293T interactomes of transiently expressed RNA-binding protein DND1: WT (replicates P9-1, P10-1, P18-1), R98A RNA binding mutant (replicates P9-2, P10-2, P18-2) and 1-235 dsRBD truncation mutant (replicates P9-3, P10-3, P18-3)
ORGANISM(S): Homo sapiens (Human) 
2022-05-30 | PXD024666 | Pride
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