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UnknownMBD5 and MBD6 couple DNA methylation to gene silencing through the J-domain protein SILENZIO.
Not available
S-EPMC8639832 | biostudies-literature
ProteomicsA genetic model for in vivo proximity labeling of the mammalian secretome
Yang R, Meyer AS, Droujinine I, Udeshi ND, Hu Y, Guo J, McMahon J, Carey DK, Xu C, Qiao F, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP. 2022. Organ functions are highly specialized and interdependent. Tissue-specific secreted factors play a critical role in organ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-16 | MSV000088848 | MassIVE
UnknownPEXEL is a proteolytic maturation site for both exported and non-exported Plasmodium proteins.
Not available
S-EPMC10900883 | biostudies-literature
TranscriptomicsDifferential regulation of SBF and MBF target genes by genotoxic stress occurs via Rad53-dependent inactivation of the MBF correpressor Nrm1
MBF and SBF transcription factors regulate a large family of coordinately expressed G1/S genes required for early cell cycle functions including DNA replication and repair. SBF is inactivated upon S phase entry by Clb/CDK whereas MBF targets are repressed by the corepressor, Nrm1. Using genome-wide ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-15 | E-GEOD-33695 | biostudies-arrayexpress
UnknownACD15, ACD21 and SLN regulate accumulation and mobility of MBD6 to silence genes and transposable elements.
Not available
S-EPMC10473691 | biostudies-literature
UnknownACD15, ACD21, and SLN regulate the accumulation and mobility of MBD6 to silence genes and transposable elements.
Not available
S-EPMC10651127 | biostudies-literature
TranscriptomicsProcessing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
Drosophila melanogaster expresses three classes of small RNAs, which are classified according to their mechanisms of biogenesis. MicroRNAs are ~22-23-nt, ubiquitously expressed small RNAs that are sequentially processed from hairpin-like precursors by Drosha/Pasha and Dcr-1/Loquacious complexes. Mic...
ORGANISM(S): Drosophila melanogaster 
2009-07-30 | E-GEOD-17171 | biostudies-arrayexpress
UnknownA photoactivatable crosslinking system reveals protein interactions in the Toxoplasma gondii inner membrane complex.
Not available
S-EPMC6795473 | biostudies-literature
TranscriptomicsProteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members
In germ cells, Piwi proteins interact with a specific class of small non-coding RNAs, piwi-interacting RNAs (piRNAs). Together, these form a pathway that represses transposable elements, thus safeguarding germ cell genomes. While basic models describe the operation of piRNA pathways, neither the pr...
ORGANISM(S): Mus musculus 
2009-07-25 | E-GEOD-17319 | biostudies-arrayexpress
ProteomicsThe interactome of the Bakers' yeast peroxiredoxin Tsa1 implicates it in the redox regulation of intermediary metabolism, glycolysis and zinc homeostasis
Zinc (Zn) is an essential nutrient supporting a range of critical processes. In the yeast Saccharomyces cerevisiae, Zn deficiency induces a transcriptional response mediated by the Zap1 activator, which controls a regulon of ~80 genes. A subset of these support zinc homeostasis by promoting zinc upt...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-09-07 | PXD060978 | Pride
Tsa1 Zap1 Saccharomyces cerevisiae Peroxiredoxin Label free ip proteomics Zinc Redox regulation 
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