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ProteomicsSvf1-GFP pulldowns from Limar et al. 2023 JCB
Svf1-GFP pulldowns compared to untegged WT cells from SILAC labelled yeast cells. See Limar et al. 2023 JCB
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-03-06 | PXD039395 | Pride
Svf1-gfp pulldowns from yeast svf1 
TranscriptomicsOncogenic Myc levels activate and repress specific genes to form characteristic expression profiles in human tumors
Myc was depleted in HeLa cells (ATCC CRL-1934) with an shRNA and the resulting expression profile changes mapped via microarrays. This study is the equivalent of E-MTAB-1524 . E-MTAB-1524 has been replaced by E-MTAB-1886.
ORGANISM(S): Homo sapiens 
2014-07-11 | E-MTAB-1886 | biostudies-arrayexpress
MetabolomicsLiquid Chromatography-High-Resolution Mass Spectrometry-Based In Vitro Toxicometabolomics of the Synthetic Cathinones 4-MPD and 4-MEAP in Pooled Human Liver Microsomes
Synthetic cathinones belong to the most often seized new psychoactive substances on an international level. This study investigated the toxicometabolomics, particularly the in vitro metabolism of 2-(methylamino)-1-(4-methylphenyl)-1-pentanone (4-MPD) and 2-(ethylamino)-1-(4-methylphenyl)-1-pentanone...
2023-11-28 | MTBLS2218 | MetaboLights
TranscriptomicsExpression profiling, siRNA mediated knockdown of PPARbeta/delta and HSP27 it HeLa cells under IL1b stimulation
HeLa cells were depeleted for PPARbeta/delta or HSP27 and treated with IL1b
ORGANISM(S): Homo_sapiens 
2013-05-14 | E-MTAB-1212 | biostudies-arrayexpress
ProteomicsIn vivo stress reporters as early biomarkers of the cellular changes associated with progeria
Study of progeria reporter mouse model using histology, proteomics and western-blotting.
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD033518 | Pride
Preclinical model Progeria Stress pathways Accelerated ageing Early biomarker 
OtherComprehensive proteome analysis of Actinoplanes sp. SE50/110 highlighting the location of proteins encoded by the acarbose and the pyochelin biosynthesis gene cluster.
Data from ProteomeXchange, PXD ID: PXD001497. Experiment: SW_Exo_G2, file: 130519_o3_p4_ao_SW_Exo_G2_8.mzml. Published as part of J Proteomics. 2015 Jul 1;125:1-16 . From the Abstract: {{i}} Acarbose is an α-glucosidase inhibitor produced by Actinoplanes sp. SE50/110 that is medically importan...
ORGANISM(S): Actinoplanes_sp_se50_110 
GPM32320019694 | GPMDB
Resource Reanalysis 
ProteomicsProteome analysis of skeletal muscle samples from a porcine model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and characterized by massive structural and functional changes of skeletal muscle tissue, leading to terminal muscle failure. In this project, proteomics data from skeletal muscle of a genetically engineered DMD pig mode...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-01-09 | PXD016003 | Pride
Duchenne muscular dystrophy Skeletal muscle Pig 
TranscriptomicsMiz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation
Miz1deltaPOZ mothers feature a lactation defect. In order to identify genes potentially regulated by Miz1 which could explain the observed phenotype and to assess the relative expression of milk protein genes and JAK-STAT pathway components, a genome-wide cDNA microarray was performed using sampl...
ORGANISM(S): Mus musculus 
2014-02-25 | E-MTAB-1718 | biostudies-arrayexpress
ProteomicsProteomic analysis of adipose tissue from a pig model of mutant INS gene induced diabetes of youth (MIDY)
To evaluate functional consequences of insulin-deficient diabetes mellitus for adipose tissue, we used a genetically engineered pig model of mutant INS gene induced diabetes of youth (MIDY). Adipose tissue samples of MIDY pigs and wild-type (WT) littermate controls were analyzed by label-free proteo...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-17 | PXD026910 | Pride
Animal model Biobank Adipose tissue Midy Pig model Diabetes Lc-ms/ms 
ProteomicsProteomic analysis of liver tissue from a pig model of mutant INS gene induced diabetes of youth (MIDY)
To evaluate functional consequences of insulin-deficient diabetes mellitus for the liver, we used a genetically engineered pig model of mutant INS gene induced diabetes of youth (MIDY). Liver samples of MIDY pigs and wild-type (WT) littermate controls were analyzed by label-free proteomics to reveal...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-11-12 | PXD011536 | Pride
Animal model Biobank Midy Pig model Diabetes Liver Lc-ms/ms 
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