Sort   by:  
 Page size 
ProteomicsProteomic analysis of liver tissue from a pig model of mutant INS gene induced diabetes of youth (MIDY)
To evaluate functional consequences of insulin-deficient diabetes mellitus for the liver, we used a genetically engineered pig model of mutant INS gene induced diabetes of youth (MIDY). Liver samples of MIDY pigs and wild-type (WT) littermate controls were analyzed by label-free proteomics to reveal...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-11-12 | PXD011536 | Pride
Animal model Biobank Midy Pig model Diabetes Liver Lc-ms/ms 
ProteomicsProteomic analysis of adipose tissue from a pig model of mutant INS gene induced diabetes of youth (MIDY)
To evaluate functional consequences of insulin-deficient diabetes mellitus for adipose tissue, we used a genetically engineered pig model of mutant INS gene induced diabetes of youth (MIDY). Adipose tissue samples of MIDY pigs and wild-type (WT) littermate controls were analyzed by label-free proteo...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-17 | PXD026910 | Pride
Animal model Biobank Adipose tissue Midy Pig model Diabetes Lc-ms/ms 
GenomicsTranscriptome profiling of mutant INS gene-induced diabetes of youth (MIDY) and wild type pig livers.
Transcriptome profiling of mutant INS gene-induced diabetes of youth (MIDY) and wild type pig livers.
PRJNA503188 | ENA
TranscriptomicsTranscriptome profiling of mutant INS gene-induced diabetes of youth (MIDY) and wild type pig livers.
Physiologically the liver is exposed to higher insulin concentrations than other organs. To evaluate functional consequences of insulin-deficient diabetes mellitus for the liver, we used a genetically engineered pig model of mutant INS gene induced diabetes of youth (MIDY). Liver samples of MIDY pig...
ORGANISM(S): Sus scrofa 
2020-01-01 | GSE122029 | GEO
UnknownDistinct states of proinsulin misfolding in MIDY.
Not available
S-EPMC8316239 | biostudies-literature
UnknownUnraveling C‑Peptide's Role in MIDY: A Structural Perspective.
Not available
S-EPMC12917636 | biostudies-literature
UnknownThe Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.
Not available
S-EPMC5518720 | biostudies-literature
UnknownDifferential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue-Multi-omics Insights From the Munich MIDY Pig Model.
Not available
S-EPMC8650062 | biostudies-literature
ProteomicsMulti-omics profiling of lung samples from genetically diabetic pigs reveals reduced ALOX15 expression and impaired eicosanoid switching as mechanisms contributing to a proinflammatory milieu
To evaluate molecular consequences of insulin-deficient diabetes mellitus for lung tissue, we used clinically diabetic pig model of mutant INS gene induced diabetes of youth (MIDY). A multi-omics analysis combining in-depth data-independent acquisition proteomics, and targeted lipidomics revealed mu...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-07-01 | PXD038014 | Pride
Lipoxygenase Lung Lipidome Diabetes Biobank Insulin deficiency Pig model Proteome 
UnknownNeural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P.
Not available
S-EPMC1856307 | biostudies-literature
Sort   by:  
 Page size