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MetabolomicsExamining the effects of cigarette smoke on mouse lens through a multi OMIC approach
Here, we report a multi OMIC (transcriptome, proteome, and metabolome) approach to investigate molecular changes in lens fiber cells (FC) of mice exposed to cigarette smoke (CS). Pregnant mice were placed in a whole-body smoke chamber and a few days later pups were born, which were exposed to CS for...
2024-03-24 | MTBLS207 | MetaboLights
UnknownStructural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.
Not available
S-EPMC5829831 | biostudies-literature
ProteomicsA rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Sirtuin 6 (SIRT6) is a deacylase and mono-ADP ribosyl transferase (mADPr) enzyme involved in multiple cellular pathways implicated in the regulation of aging and metabolism. Targeted sequencing identified a SIRT6 allele containing two linked substitutions (N308K/A313S) as enriched in Ashkenazi Jewis...
ORGANISM(S): Homo sapiens (Human) 
2022-10-21 | PXD035689 | Pride
Lmna Centenarian Longevity Sirt6 Adp-ribosylation Aging 
UnknownA rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Not available
S-EPMC9627671 | biostudies-literature
ProteomicsDynamic protein acetylation changes in E. coli (carbon overflow)
Not available
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2015-03-09 | MSV000079073 | MassIVE
UnknownA rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Not available
S-SCDT-EMBOJ-2021-110393 | biostudies-other
UnknownAssociation of Common Genetic Variants in the CPSF7 and SDHAF2 Genes with Canine Idiopathic Pulmonary Fibrosis in the West Highland White Terrier.
Not available
S-EPMC7349241 | biostudies-literature
UnknownRehabilitation Interventions to modify endocrine-metabolic disease risk in Individuals with chronic Spinal cord injury living in the Community (RIISC): A systematic review and scoping perspective.
Not available
S-EPMC5778937 | biostudies-literature
UnknownCrystal structure of nonphosphorylated receiver domain of the stress response regulator RcsB from Escherichia coli.
Not available
S-EPMC5119572 | biostudies-literature
MetabolomicsStage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA.

METHODS: We investi...

2023-01-31 | MTBLS5297 | MetaboLights
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