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UnknownPatient-reported outcomes of upadacitinib versus abatacept in patients with rheumatoid arthritis and an inadequate response to biologic disease-modifying antirheumatic drugs: 12- and 24-week results of a phase 3 trial.
Not available
S-EPMC9229430 | biostudies-literature
TranscriptomicsPancreatic Cancer HPAF/CD18 cells: Ecd knockdown vs Scrambled
Purpose: To study the expression and function of a novel cell cycle regulatory protein, human ecdysoneless (Ecd), during pancreatic cancer (PC) pathogenesis. Experimental Design: Immunohistochemical expression profiling of Ecd was done in non-neoplastic normal pancreatic tissues and pancreatic ducta...
ORGANISM(S): Homo sapiens 
2012-08-09 | E-GEOD-39988 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of Mycobacterium tuberculosis to lung surfactant
This study uses microarray analyses to examine gene expression profiles for Mycobacterium tuberculosis (Mtb) induced by exposure in vitro to bovine lung surfactant preparations that vary in apoprotein content: (i) whole lung surfactant (WLS) containing the complete mix of endogenous lipids and surfa...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-18 | E-GEOD-14005 | biostudies-arrayexpress
ProteomicsHMGB1 interactome in prostate and ovarian cancer cells treated with cisplatin
Cisplatin is used in chemotherapy of prostate, ovary and other cancer types but unfortunately the efficiency of cisplatin treatment is frequently hampered by acquired resistance. The cytotoxic effect of cisplatin has been attributed to its binding to DNA. HMGB1 is able to bind to cisplatin-DNA adduc...
ORGANISM(S): Homo sapiens (Human) 
2021-11-01 | PXD026309 | Pride
Pc-3 Prostate cancer Ovarian cancer Skov-3 Cisplatin Hmgb1 Interactome 
TranscriptomicsGene Expression in Peripheral Blood Leucocytes in Monozygotic Twins Discordant for Chronic Fatigue
Background. Chronic fatiguing illness remains a poorly understood syndrome of unknown pathogenesis. We attempted to identify biomarkers for chronic fatiguing illness using microarrays to query the transcriptome in peripheral blood leukocytes. Methods. Cases were 44 individuals who were clinically ev...
ORGANISM(S): Homo sapiens 
2009-05-12 | E-GEOD-16059 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Clostridium difficile strains to identify markers of different ribotypes
Clostridium  difficile  (C. difficile) strains belonging to PCR ribotype 027, PFGE type NAP1, REA type B1 and toxinotype III, termed NAP1/027, have been implicated in the increased frequency of outbreaks of Clostridium difficile-associated diarrhoea (CDAD) in North America and Europe. The NAP1/027 s...
ORGANISM(S): Clostridium difficile 
2010-07-01 | E-MTAB-162 | biostudies-arrayexpress
UnknownMR Imaging Correlates for Molecular and Mutational Analyses in Children with Diffuse Intrinsic Pontine Glioma.
Not available
S-EPMC7228178 | biostudies-literature
MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
TranscriptomicsNon-invasive Analysis of the Airway Transcriptome Discriminates Clinical Phenotypes of Asthma
BACKGROUND: Evaluation of the airway transcriptome may reveal patterns of gene expression that are associated with clinical phenotypes of asthma. To define transcriptomic endotypes of asthma (TEA) we analyzed gene expression in induced sputum that correlate with phenotypes of disease. METHODS: Ge...
ORGANISM(S): Homo sapiens 
2014-04-07 | E-GEOD-56396 | biostudies-arrayexpress
UnknownAnatabine supplementation decreases thyroglobulin antibodies in patients with chronic lymphocytic autoimmune (Hashimoto's) thyroiditis: a randomized controlled clinical trial.
Not available
S-EPMC3928963 | biostudies-literature
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