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UnknownMechanical Behavior of Human Cancellous Bone in Alveolar Bone under Uniaxial Compression and Creep Tests.
Not available
S-EPMC9457185 | biostudies-literature
UnknownConstruction of a high-density bin-map and identification of fruit quality-related quantitative trait loci and functional genes in pear.
Not available
S-EPMC9437719 | biostudies-literature
GenomicsMethylation disorder in CLL
We performed RRBS and WGBS on primary human chronic lymphocytic leukemia and normal healthy donor B cell samples Due to patient privacy concerns, the raw data is being made available via controlled access in dbGaP (http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000435.v1.p1)....
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-58889 | biostudies-arrayexpress
ProteomicsPterosin B treatment protect cells from glutamate-induced cytotoxicity
The prevalence of neurodegenerative diseases is rapidly increasing with the aging trend of global populations, severely threatening human health and burdening society. However, to date, there is no effective treatment able to halt the progression or cure the diseases. Here, We aim to develop effecti...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-01 | PXD030396 | Pride
Ros Neuroprotective natural products Glutamate excitotoxicity Mitochondria membrane potential 
ProteomicsTemozolomide Induces Glioblastoma Dedifferentiation into Highly Malignant Stem-like Cells Through Senescence-Associated Reprogramming via HIF1α/HIF2α Regulation
A critical issue is that recurrent glioblastoma multiforme (GBM) after temozolomide (TMZ) exposure becomes more malignant, exhibiting higher invasion and stemness than the primary tumor. However, the detailed mechanism remains to be elucidated. While the majority of GBM cells succumb to TMZ treatmen...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058156 | Pride
Temozolomide Glioblastoma 
MetabolomicsAlterations in the Gut Microbiota and Metabolomics of Seafarers after a Six-Month Sea Voyage

Maintaining the health of seafarers is a difficult task during long-term voyages. Little is known about the corresponding changes in the gut microbiome-host interaction. This study recruited 30 seafarers undertaking a 6-month voyage and analyzed their gut microbiota using 16S rRNA gene sequencing...

2022-09-29 | MTBLS5335 | MetaboLights
MetabolomicsProduction of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027

Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
TranscriptomicsTranscription profiling of mouse wild type and Pias1 null cells in response to IFN treatments to study the effect of PIAS1 on interferon (IFN) signaling pathway
Microarray analysis was designed to study the effect of PIAS1 on interferon (IFN) signaling pathway by comparing the gene activation profiles of wild type and Pias1 null cells in response to IFN treatments. Microarray analysis was performed essentially following the manufacturer's instructions (Affy...
ORGANISM(S): Mus musculus 
2007-10-10 | E-GEOD-1552 | biostudies-arrayexpress
ProteomicsHoneybee brain neuropeptides LC-MSMS
To explore brain neuropeptidic functions in behavioral regulation, a label-free quantitative strategy was employed to compare neuropeptidomic variations between behavioral phenotypes (nurse bees, nectar foragers, and pollen foragers) and the two honeybee species (Apis mellifera ligustica and Apis ce...
ORGANISM(S): Apis mellifera (Honeybee) 
2021-09-09 | PXD018713 | Pride
Lc-msms Brain Honeybee Neruopeptide 
MetabolomicsGut microbiota-derived butyric acid protected against secondary brain injury after SAH by inhibiting neuronal pyroptosis and regulating gut microbiota composition (Murine assays)

BACKGROUND: Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular disease with a poor prognosis. Accumulating studies have reported that gut microbiota contributes to the pathophysiology of several central nervous system diseases. However, whether SAH can change gut micr...

2024-07-09 | MTBLS9100 | MetaboLights
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