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The aim of this project is to use an integrated approach involving label-free strategy, HPLC fractionation and LC-MS/MS to quantify the dynamic changes of the whole proteome of Mouse Cell(MEF and R1 cells).
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD034181 | Pride
We hypothesized that uncovering interactions between Pfkp and other proteins could help resolve the mechanism whereby Pfkp regulates germ layer differentiation. Towards this, Pfkp was immunoprecipitated from mESCs and mass spectrometry analysis used to identify a number of potential Pfkp-interacting...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-23 | PXD038944 | Pride
CHKA phosphorylates PML at Tyr339 to promote its cytoplasmic localization; cytoplasmic PML then induces WIPI2 SUMOylation at Lys281/283, blocking HUWE1-mediated degradation. Stabilized WIPI2 enhances autophagic flux and supports tumor cell survival under metabolic stress.
ORGANISM(S): Homo Sapiens 
2026-03-03 | PXD075116 |
Fungal cell walls undergo continual remodeling during hyphal growth, development, infection and adaptation to environmental stress. Cell wall remodeling generates 1,3-glucan fragments by diverse endo-glycosyl hydrolases (GH), which are well-known pathogen-associated molecular patterns (PAMPs). How f...
ORGANISM(S): Magnaporthe 
2023-08-14 | PXD044578 |
We propose that abnormal DNA content in tetraploid cells can alter the gene expression profile, contributing to the cellular transformation. To test this hypothesis, we employ mRNA microarray to compare the gene expression profile in transformed tetraploid cells with that in the parent diploid cells...
ORGANISM(S): Mus musculus 
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