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MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
TranscriptomicsCharacterization of the transcriptomes of genetically diverse Listeria monocytogenes exposed to hyperosmotic and low temperature conditions
A screening process was used to determine hyperosmotic as well as cold stress tolerance of a diverse set of Listeria monocytogenes strains and was based on the capacity to grow at sub lethal levels of NaCl and 4M-BM-0C. Analysis of gene expression in cells adapted to cold and hyperosmotic stress rev...
ORGANISM(S): Listeria monocytogenes 
2013-05-04 | E-GEOD-46612 | biostudies-arrayexpress
TranscriptomicsIdentification of the phosphotransacetylase (pta) and acetate kinase (ackA) regulons in Streptococcus mutans UA159
Transcriptional comparisons between wild-type Streptococcus mutans UA159 and two mutant strains (M-bM-^HM-^FackA and M-bM-^HM-^FackA pta). On growth condition in defined FMC medium, WT vs. either M-bM-^HM-^FackA or M-bM-^HM-^FackA pta mutants. Biological replicates: 10 control, 5 each mutant, indepe...
ORGANISM(S): Streptococcus mutans UA159 
2013-05-11 | E-GEOD-46835 | biostudies-arrayexpress
ProteomicsMethanobacterium thermautotrophicus temperature-stress LC-MSMS
Methanothermobacter thermautotrophicus is a model thermophilic hydrogenotrophic methanogen. The life and survival of M. thermautotrophicus is highly influenced by the availability of nutrients and temperature. To learn about adaptation mechanisms evolved by the archaea to cope with drastic temperatu...
ORGANISM(S): Methanobacterium 
2018-10-02 | PXD006685 | Pride
Temperature-stress Lc-msms Methanobacterium thermautotrophicus 
ProteomicsModification of Human MAVS protein
This modification plays a critical role in regulating protein function and cellular processes.MAVS succination sites were identified using mass spectrometry (MS). Identify succination sites of human MAVS protein.
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD061060 | Pride
Mavs Lc-ms 
TranscriptomicsIGR_BLADDER_GE_STUDY_JA
Background: Although histology is the corner stone for decision analysis in bladder cancer, it still needs refinement and new tools to better identify tumours with the highest risk of progression or recurrence. Objective: We designed a prospective study to evaluate whether microarray analysis could ...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-MTAB-993 | biostudies-arrayexpress
ProteomicsEGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association
EGF is one of the most well-characterized growth factors and plays a crucial role in cell proliferation and differentiation. EGFR has been extensively explored as a therapeutic target against multiple types of cancers, such as lung cancer and glioblastoma. Recent studies have established a connectio...
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD031593 | Pride
Epidermal growth factor (egf) Phosphotyrosine binding protein O-glcnacylation Pyruvate kinase m2 (pkm2) Phosphorylation O-glcnac transferase (ogt) 
MetabolomicsMulti-country metabolic signature discovery for chicken health classification

INTRODUCTION: To decrease antibiotic resistance, their use as growth promoters in the agricultural sector has been largely abandoned. This may lead to decreased health due to infectious disease or microbiome changes leading to gut inflammation.

OBJECTIVES: ...

2023-08-08 | MTBLS5065 | MetaboLights
ProteomicsPKM2 functions as a histidine kinase to phosphorylate PGAM1 to increase glycolysis shunts in cancer-Cellular lipid level assessment
Phosphoglycerate mutase 1 (PGAM1) is a key node enzyme that diverts the metabolic reactions from glycolysis into its shunts to support macromolecule biosynthesis for rapid and sustainable cell proliferation. It is prevalent that PGAM1 activity is upregulated in various tumors; however, the underlyin...
ORGANISM(S): Homo sapiens (Human) 
2024-03-21 | PXD049310 | Pride
Glycolysis shunts Pyruvate kinase m2 (pkm2) Histidine kinase Phosphorylation Phosphoglycerate mutase 1 (pgam1) 
ProteomicsIdentification of phosphorylation sites of BAG3
HEK293 cells were cultured in two 10-cm dishes and transfected with BAG3-FLAG as well as Myc vector, CaMKIIβ(D-S)-Myc, and CaMKIIδ(D-S)-MYC, respectively. After the cells were transfected for 24 h, they were treated with the indicated regent. The cells were lysed with NP-40 alternative cell lysis bu...
ORGANISM(S): Homo sapiens (Human) 
2024-08-20 | PXD054722 | Pride
Phosphorylation sites Bag3 Human 
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