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TranscriptomicsQuantitative Analysis of Wild Type(wt) and Setd2 knockout(ko) mESCs Transcriptomes [RNA-Seq]
Purpose: This study aimed at exploring the deregulated genes in setd2 knockout mESCs compared with wt, more particularly to find the mechanism controlled by setd2,which was required for endoderm differentiation. Methods: Setd2 wt and ko mESCs were generated by deep sequencing, using Illumina GAIIx. ...
ORGANISM(S): Mus musculus 
2014-10-14 | E-GEOD-54932 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression pattern between Wild-type and Setd2 knockout mESCs [Affymetrix]
SETD2/HYPB has been known as a histone H3K36 specific methyltransferase. However, its roles in physiology such as development and cellular function remain unclear. In this study, using mESCs as cellular model, we show that Setd2 mainly regulates differentiation of murine embryonic stem cells (mESCs)...
ORGANISM(S): Mus musculus 
2014-10-14 | E-GEOD-54931 | biostudies-arrayexpress
ProteomicsDiscovery of Non-Canonical Peptides Derived from Novel Small Open Reading Frames as MHC-I Epitopes
Immunopeptides that are translated in cells and presented at the cell surface by major histocompatibility complex (MHC) mole-cules are important epitopes in basic Immunology and translational cancer immunotherapy. While most of the reported immuno-peptides are derived from protein coding sequence, t...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD024415 | Pride
Price Ribotish Sorf Non-canonical peptides Lc-ms Mhc-i 
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
ProteomicsProteomic analysis of the four rat models of depression
Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The pathogenesis of MDD remained unclear, and it may be associated with exposure to different stressors. Most previous studies have focused on molecular changes in a single stress-induced depression model, which limited ...
ORGANISM(S): Rattus Norvegicus 
2023-05-22 | PXD043285 |
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