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Gene expression during cellular differentiation is coordinated by combinatorial interactions between transcription factors (TFs) and cofactors at promoters and enhancers. The “master TF” GATA1 coordinates gene transcription in a subset of hematopoietic lineages, including erythroid, megakaryocytic, ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-10 | PXD076443 | Pride
Fz4 and Fz8 cooperate in regulating the branching morhpogenesis of the developing kidney during mouse embryonic development, hence determines the eventual kidney size. We used microarrays to study the global gene expression profiles regulated by Fz4 and Fz8 signaling during early kidney development,...
ORGANISM(S): Mus musculus 
Fz4 and Fz8 cooperate in regulating the branching morhpogenesis of the developing kidney during mouse embryonic development, hence determines the eventual kidney size. We used microarrays to study the global gene expression profiles regulated by Fz4 and Fz8 signaling during early kidney development,...
ORGANISM(S): Mus musculus 
Metastatic ability correlates well with the malignance of esophageal squamous cell carcinoma (ESCC). Gaps remain in elucidating the multi-layered interaction networks during ESCC metastasis in the premise of lysine lactylation (Kla) is of crucial importance. Here, we performed an integrated proteoge...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD063341 | Pride
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