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To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to systematic proteomic.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD037295 | Pride
In total, 5,840 protein groups were identified, among which 5,188 proteins were quantified. The fold-change cutoff was set when proteins with quantitative ratios above 1.5 or below 0.667 are deemed significant. Among the quantified proteins, 95 proteins are up-regulated and 155 proteins are down-reg...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-11-12 | PXD011814 | Pride
Hepatocellular carcinoma is one of the most frequently diagnosed cancers in the world. Post-translational modifications (PTMs) play an essential role during cancer development. Phosphorylation is an important PTMs. To identify the modifications of phosphorylation in HCC, a multiplexed tandem mass ta...
ORGANISM(S): Homo sapiens (Human) 
2021-01-14 | PXD013934 | Pride
Posttranslational modification (PTM) refers to the process of the covalent processing of translated proteins, as well as the activities and functions of proteins, and it is involved in almost all cellular pathways and processes. Lysine crotonylation (Kcr) is a recently identified PTM and plays a key...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD012966 | Pride
Pressure ulcers (PU) is a complex and serious clinical problem. Deep tissue injury is either the outcome or the trigger of deep PU. However, the cellular and molecular mechanisms that contribute to the pathogenesis of deep PU remain unclear. In this study, the degeneration characteristics, increased...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD009512 | Pride
We analyzed the features of proteome profiling of eelgrass seed germination stimulated by low salinity based on 4D lable-free proteomic analysis. The molecular mechanism of eelgrass seed germination kinetics revealed in this study is of great significance to the study of seagrass seed biology.
ORGANISM(S): Zostera Marina 
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