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ProteomicsIdentification of ASC-interacting proteins
To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we infected primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with the bacterium Francisella novicida to induce AIM2 inflammasome activation and then performed ASC IP-MS to identify proteins that...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-29 | PXD052497 | Pride
Asc Francisella novicida Inflammasome Bmdm Mouse 
ProteomicsIdentification of ASC-interacting proteins
To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we treated primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with LPS (500 ng/ml) and ATP (5 mM) to activate NLRP3 inflammasome activation and then performed ASC IP-MS to identify proteins that i...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD054933 | Pride
Asc Mouse bmdm Lps and atp Nlrp3 inflammasome 
ProteomicsEnhancer DNA pull-down of proteins extracted from PA2 tissue of mouse E11.5 embryos
Enhancers, through the combinatorial action of transcription factors (TFs), dictate both the spatial specificity and the levels of gene expression, and their aberrations can result in diseases. While HMX1 downstream enhancer is associated to ear malformations, the mechanisms underlying bilateral con...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-28 | PXD063373 | Pride
Dna pull-down Mouse e11.5 embryos 
UnknownRivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
Not available
S-EPMC6662613 | biostudies-literature
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