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ProteomicsProteomic analysis of brain tissue from ducks with meningitis caused by Riemerella anatipestifer infection
To investigate the key molecules or proteins involved in Riemerella anatipestifer’s penetration of the blood-brain barrier and the subsequent development of duck meningitis, a duck meningitis model was established and characterized. Duckling brain tissues were collected and analyzed using 4D label-f...
ORGANISM(S): Anas Nesiotis 
2024-06-07 | PXD052981 |
ProteomicsProteomics detection of mouse embryonic 17.5 dpc cultured ovaries in vitro
In this project, the ovaries of mice at 17.5 dpc embryonic stage were collected, and KN93, an inhibitor of CAMKII, and IWP2, an inhibitor of Wnt5a, were added for in vitro culture. Proteins affected by KN93 and IWP2, which were regulated by CAMKII and Wnt5a, were detected by proteomics technology, s...
ORGANISM(S): Mus Musculus 
2022-07-07 | PXD035136 |
ProteomicsStructural basis of RNA polymerase complexes in African swine fever virus
African swine fever virus is highly contagious and causes a fatal infectious disease in pigs, resulting in a significant global impact on pork supply. The African swine fever virus RNA polymerase serves as a crucial multifunctional protein complex responsible for genome transcription and regulation....
ORGANISM(S): African swine fever virus 
2025-02-14 | PXD058133 | Pride
Protein African swine fever virus Lc-msms 
TranscriptomicsmRNA expression data from AG-haESC, E14 and MEF
Haploid cells are amenable for genetic analysis because they contain only one set of chromosomes.Here,we report the derivation of haESCs from androgenetic blastocysts. These cells, which we designated AG-haESCs, express classical ESC markers, are pluripotent, and contribute to various tissues includ...
ORGANISM(S): Mus musculus 
2012-04-26 | E-GEOD-35785 | biostudies-arrayexpress
GenomicsAscorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.
DNA demethylation occurs in multiple cellular processes but its regulation is poorly understood. Here we report that a vital nutrient factor ascorbic acid (AA), or vitamin C (Vc), induces DNA demethylation in mammalian cells. The levels of active 5mC oxidation products, 5-formylcytosine and 5-carbox...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-43262 | biostudies-arrayexpress
ProteomicsProteomics and network pharmacology of Ganshu Nuodan capsules in the prevention of alcoholic liver disease
A mouse model of acute alcohol liver disease (ALD) induced by intragastric administration of 50% alcohol was used to evaluate the hepatoprotective effect of Ganshu Nuodan. The chemical constituents of Ganshu Nuodan were comprehensively identified by UPLC-QTOF/MS, and then its pharmacodynamic materia...
ORGANISM(S): Mus Musculus 
2023-09-08 | PXD045221 |
ProteomicsP.aeruginosa PAO1+Pht Tandem Mass Tag (TMT)-based quantitative proteomic analysis
To study the changes in the proteomics profile of P. aeruginosa PAO1 upon Pht addition, TMT was used as the labeling strategy for comparative quantitative proteomic analysis.
ORGANISM(S): Pseudomonas Aeruginosa 
2022-03-18 | PXD032384 |
Proteomics4D label-free quantitative proteomics analysis of collagen-induced arthritis rats
4D label-free quantitative proteomics was performed to analysis the changes of protein expression in synovial tissues between Normal control group, Model control group and JTQBG treated group.
ORGANISM(S): Rattus Norvegicus 
2024-02-23 | PXD050056 |
ProteomicsFunctional analysis of Salix purpurea genes support roles for ARR17 and GATA15 as master regulators of sex determination
The Salicaceae family is of growing interest in the study of dioecy in plants because the sex determination region (SDR) has been shown to be highly dynamic, with differing locations and heterogametic systems across taxa. Previous studies investigating the mechanisms regulating sex in the genus Sali...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2023-02-01 | MSV000091180 | MassIVE
ProteomicsCardiomyocyte-Derived HSPB1 Regulates TGF-β1 Maturation and Inhibits Endothelial-to-Mesenchymal Transition in Myocardial Fibrosis after Infarction
Myocardial fibrosis is a major contributor to heart failure after myocardial infarction (MI), primarily driven by endothelial-to-mesenchymal transition (EndoMT). Heat shock protein B1 (HSPB1) has cardioprotective functions, but its role in MI-induced fibrosis remains unclear. Here, we show that card...
ORGANISM(S): Homo Sapiens 
2025-12-22 | PXD072325 |
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