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ProteomicsHST-MRM-MS: A Novel High-Sample-Throughput Multiple Reaction Monitoring Mass Spectrometric Method for Multiplex Absolute Quantitation of Hepatocellular Carcinoma Serum Biomarker
Absolute quantification of clinical biomarkers by mass spectrometry (MS) has been challenged due to low sample-throughput of current multiple reaction monitoring (MRM) methods. For this problem to be overcome, in this work, a novel high-sample-throughput multiple reaction monitoring mass spectrometr...
ORGANISM(S): Homo Sapiens 
2020-02-23 | PXD040708 |
ProteomicsChemical labeling for fine mapping of IgG N-glycosylation by ETD-MS
Immunoglobulin G (IgG), which contains four subclasses (IgG1-4), is one of the most important class of glycoproteins in immune system. Because of its importance in immune system, a steady increase of interest in developing IgG as biomarker or biotherapeutic agents for the treatment of diseases has b...
ORGANISM(S): Homo sapiens (Human) 
2019-08-26 | PXD014713 | Pride
Chemical labeling Igg Glycosylation Glycopeptides Electron transfer dissociation (etd) mass spectrometry 
UnknownEvery road leads to Rome: therapeutic effect and mechanism of the extracellular vesicles of human embryonic stem cell-derived immune and matrix regulatory cells administered to mouse models of pulmonary fibrosis through different routes.
Not available
S-EPMC9006546 | biostudies-literature
ProteomicsA Chemical Proteomics Approach for Global Mapping of Functional Lysines on Cell Surface of Living Cell
Cell surface proteins are responsible for many crucial physiological roles, and they are also the major category of drug targets as the majority of therapeutics target membrane proteins on the surface of cells to alter cellular signaling. How-ever, despite its great significance, ligand discovery ag...
ORGANISM(S): Homo Sapiens 
2024-03-01 | PXD042888 |
ProteomicsTMT-based proteome and phosphoproteome profiling of control and GPR146 knockdown SGBS cells
This dataset contains quantitative proteome and phosphoproteome profiles of control and GPR146 knockdown SGBS human preadipocyte cells. Cells were processed for tandem mass tag (TMT)–based multiplexed quantitative mass spectrometry, with parallel analysis of total proteome input samples and TiO2-enr...
ORGANISM(S): Homo sapiens (Human) 
2026-02-19 | PXD074087 | Pride
Phosphoproteomics Gpr146 Sgbs cells Orbitrap Tmt6plex Lc-ms/ms 
UnknownGlobal burden and inequality of iron deficiency: findings from the Global Burden of Disease datasets 1990-2017.
Not available
S-EPMC8933942 | biostudies-literature
ProteomicsComprehensive N-Glycomics Profiling of Urinary Extracellular Vesicles Identifies a Novel Biomarker Panel for Diagnosis of Bladder Cancer
Bladder cancer (BC) is the most common urologic malignancy, facing enormous diagnostic challenges.Urinary extracellular vesicles (EVs) is a particularly promising source for developing diagnostic markers for bladder cancer because of the direct contact between urine and bladder. We investigate bioma...
ORGANISM(S): Homo Sapiens 
2024-11-14 | PXD057882 |
UnknownImmunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis.
Not available
S-EPMC7296193 | biostudies-literature
ProteomicsMass spectrometry identification of PPARγ methylation sites
Purified recombinant PPARγ-Flag and PRMT4-His were used for in vitro methyltransferase assay.We separated purified methylated PPARγ proteins by SDS-PAGE, visualized them by staining with Coomassie blue, protein lanes were cut into pieces about 1 mm3, and followed further destained.
ORGANISM(S): Homo Sapiens 
2022-06-27 | PXD034929 |
ProteomicsIdentification of TIRR ubiquitination site by mass spec
Identification of TIRR ubiquitination site in 293T cells by mass spec
ORGANISM(S): Homo Sapiens 
2024-08-29 | PXD055432 |
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