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ProteomicsMulti-omics analysis of natural aging mouse liver
Multi-omics analysis is relatively rare in aging research and has not been used for aging liver study by now. Here, we performed metabolome, proteome and acetylome with livers of 2-month-old and 18-month-old mice.
ORGANISM(S): Mus Musculus 
2020-03-11 | PXD018003 |
ProteomicsThe Omicron variant-associated cardiac injury mechanism in rhesus macaques is revealed by a proteome and phosphoproteomic map ( phosphoproteomic and proteome data)
Here, we identified proteins and phosphosites that were differentially regulated during infection with the Omicron variant using cardiac proteomics and phosphoproteomics. Our results demonstrate alterations in the global landscape of the cardiac proteome and phosphoproteome following infection with ...
ORGANISM(S): Macaca Mulatta 
PXD051632 |
ProteomicsQuantitative proteomics of human lung
The proteome in human lung was identified by mass spectrometry and quantified by label free method
ORGANISM(S): Homo Sapiens 
PXD036439 |
ProteomicsGlobal Profiling of the Lysine Lactylation in Human Lung
LC-MS/MS for global profiling of lactylation in human lung under normal physiological conditions
ORGANISM(S): Homo Sapiens 
PXD036307 |
ProteomicsLysine Succinylation in Human Lungs
In this study, we performed LC-MS/MS for global profiling of succinylation in 6 human lungs under normal physiological conditions. Our work will help for further study the function of succinylation modification in various physiology and pathology, as well as the energy metabolism and the regulation ...
ORGANISM(S): Homo Sapiens 
2021-11-02 | PXD029533 |
ProteomicsPhosphoproteome profiling of mouse liver during normal aging
Totally, fourteen two-month-old mice were used in the young group and ten eighteen-month-old mice were used in the old group. Their livers were detached for phosphoproteome analysis.
ORGANISM(S): Mus Musculus 
2021-02-21 | PXD024270 |
ProteomicsMulti-organ proteomic and phosphoproteomic landscape of K18-hACE2 mice infected with SARS-CoV-2
Eight 10-week-old female K18-hACE2 mice were equally divided into control (n = 4) and virus-infected group (n = 4). Mice in the virus-infected group were challenged with 10^5 median tissue culture infective dose (TCID50) of SARS-CoV-2 virus by intranasal inoculation and mice in the control group wer...
ORGANISM(S): Mus Musculus 
PXD035474 |
ProteomicsGlobal profiling of protein lactylation in Caenorhabditis elegans (label-free quantitative proteomic data)
We identified 1836 Class I (locnalization probabilities > 0.75) lactylated sites in 487 proteis,This study establish the first lactylome database in Caenorhabditis elegans and provides a basis for studying the role of lactylation. In addition, it provides a evidence for the existence of lactylation ...
ORGANISM(S): Caenorhabditis Elegans 
PXD041277 |
ProteomicsGlobal profiling of lysine ubiquitylation in human hypothalamus
In this study, we employed LC‒MS/MS to generate a comprehensive profile of ubiquitylation in the human hypothalamus under normal physiological conditions. Our findings will contribute to further exploration of the role of ubiquitylation in various physiological and pathological processes, particular...
ORGANISM(S): Homo Sapiens 
2024-02-24 | PXD050124 |
ProteomicsGlobal lysine crotonylation profiling in the livers of mice
Crotonylation (Cr) is a novel post-transcriptional modification with the potential to regulate multiple biological processes. In order to improve the crotonylation dataset for further study, we performed LC-MS/MS with mouse liver samples to obtain the in vivo crotonylome. Totally, we identified 4607...
ORGANISM(S): Mus Musculus 
2020-01-19 | PXD015645 |
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