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ProteomicsRAN, TDP43 and G3BP1 mRNA form a complex
To identify the candidate that directly stabilizes G3BP1 mRNA, the enriched proteins pulled down by G3BP1 probes and anti-RAN antibody were subjected to mass spectrometry (MS) analysis
ORGANISM(S): Homo Sapiens 
2024-10-01 | PXD056577 |
UnknownUSP13 dictates Ran turnover and vulnerability to ferroptosis in diffuse large B cell lymphoma (DLBCL).
Not available
S-EPMC12663190 | biostudies-literature
UnknownThe noncanonical RNA-binding protein RAN stabilizes the mRNA of intranuclear stress granule assembly factor G3BP1 in nasopharyngeal carcinoma.
Not available
S-EPMC11635782 | biostudies-literature
UnknownThe Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules.
Not available
S-EPMC6386614 | biostudies-literature
UnknownDiscovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
Not available
S-EPMC4232217 | biostudies-literature
TranscriptomicsThe Role of the E2F1 transcription factor in the innate immune response to systemic LPS [mRNA]
Our recent study of gene expression in mice treated with LPS systemically identified the E2F1 transcription factor as a novel regulator of innate immune response in lung, liver, and spleen tissue. Our follow up studies showed that RNAi-mediated inhibition or E2F1 gene deficiency lead to reduced infl...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-33901 | biostudies-arrayexpress
UnknownThe RNA m5C modification in R-loops as an off switch of Alt-NHEJ.
Not available
S-EPMC10542358 | biostudies-literature
TranscriptomicsGene expression profiles of LPS-stimulated RAW264.7 macrophages overexpressing Tbc1d23 novel innate immune gene
We previously identified Tbc1d23 as a candidate novel regulator of innate immunity using comparative genomics RNAi screens in C. elegans and mouse macrophages. Using mice with an engineered knockout mutation in Tbc1d23 and macrophages engineered to overexpress Tbc1d23, we now show that Tbc1d23 is a ...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-30840 | biostudies-arrayexpress
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
OtherMarker for type VI secretion system effectors
Data from PeptideAtlas, [[http://www.peptideatlas.org/PASS/PASS00442 PASS00442]]. File: QEX1_C01215_R3.mzml. From PeptideAtlas: {{i}} Vibrio parahaemolyticus cells were grown in minimal media (M9 + 3% NaCl) with addition of 5 uM phenamil (to simulate growth on surface) for 5 hours in triplicates, an...
ORGANISM(S): Vibriophage_vp4_uid15449,vibriophage_vpv262_uid14316,vibrio_phage_fs1_uid14227,vibrio_phage_fs2_uid14088,vibrio_phage_k139_uid14144,vibrio_phage_kappa_uid28503,vibrio_phage_ksf_1phi_uid14562,vibrio_phage_kvp40_uid14416,vibrio_phage_n4_uid42785,vibrio_phage_vejphi_uid38367,vibrio_phage_vf12_uid14385,vibrio_phage_vf33_uid14384,vibrio_phage_vfo3k6_uid14093,vibrio_phage_vfo4k68_uid14094,vibrio_phage_vgjphi_uid14279,vibrio_phage_vhml_uid14234,vibrio_phage_vp2_uid14473,vibrio_phage_vp5_uid14382,vibrio_phage_vp882_uid18851,vibrio_phage_vp93_uid37885,vibrio_phage_vsk_uid14337, Vibrio_parahaemolyticus_rimd_2210633 
GPM32320000099 | GPMDB
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