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ProteomicsStromal Interaction Molecule 1 Maintains Beta Cell Identity and Function in Female Mice through Preservation of G Protein-Coupled Estrogen Receptor 1 Signaling
Loss of pancreatic Beta cell mass, identity, and function contribute to the development of diabetes. Here, we show that the endoplasmic reticulum (ER) calcium sensor, stromal interaction molecule 1 (STIM1), is critical for the maintenance of Beta cell function in female mice. When mice with Beta cel...
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2022-07-20 | MSV000089927 | MassIVE
Proteomics4D label-free quantitative proteomics analysis of collagen-induced arthritis rats
4D label-free quantitative proteomics was performed to analysis the changes of protein expression in synovial tissues between Normal control group, Model control group and JTQBG treated group.
ORGANISM(S): Rattus Norvegicus 
2024-02-23 | PXD050056 |
ProteomicsA global multi-regional proteomic map of the human cerebral cortex
In this study, four groups of the iTRAQ quantification experiment using 2D-LC-MS/MS analysis, one group of the label-free quantification experiment using 2D-LC-MS/MS analysis, one group of the PRM quantification experiment of the human brain tissue were included. Therefore, six subprojects are incl...
ORGANISM(S): Homo Sapiens 
2021-03-09 | PXD024613 |
ProteomicsA Comprehensive Proteomics Analysis Reveals Dynamic Phenotypes of Tumor-associated Macrophages and Their Precursor Cells in Tumor Progression
Tumor-associated macrophages (TAMs) are key regulators in tumor progression. Although a role of bone marrow-derived monocytes (Mons) as TAM precursors has been revealed, the dynamic phenotypes of both TAMs and Mons regulated by the tumor microenvironment remain unclear. Here, we constructed an optim...
ORGANISM(S): Mus Musculus 
2023-10-30 | PXD046492 |
ProteomicsLRRC71 is essential for sperm motility, fertilization and male fertility
Although sperm supply half the genomic material necessary for generating viable offspring in sexual reproduction, the core molecular mechanisms underlying their formation remain largely unelucidated. Here, we demonstrate that leucine-rich repeat-containing 71 (LRRC71) is essential for spermatogenesi...
ORGANISM(S): Mus Musculus 
PXD077837 |
ProteomicsGenetic origin and evolution of bioluminescence of fireflies
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Lamprigera Yunnana 
PXD015226 |
ProteomicsThe origin and evolution of bioluminescence of fireflies
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Luciola Terminalis 
PXD015227 |
ProteomicsThe proteome data of human mesenchymal stem cell derived from healthy donors
The protein samples stored at -80 °C were thawed and treated with lysis buffer (8M urea, 1% protease inhibitor, 50mM NH4HCO3) for 5 minutes in room temperature. After ultrasonic cracking on ice and centrifugation at 14000g for 10 min at 20 °C, the amount of total protein of each MSC sample was detec...
ORGANISM(S): Homo Sapiens 
2023-06-12 | PXD033812 |
ProteomicsThe proteome data of extracellular vesicles derived from human umbilical cord and bone marrow mesenchymal stem cells
The protein samples stored at -80 °C were thawed and treated with lysis buffer (8M urea, 1% protease inhibitor, 50mM NH4HCO3) for 5 minutes in room temperature. After ultrasonic cracking on ice and centrifugation at 14000g for 10 min at 20 °C, the amount of total protein of each MSC sample was detec...
ORGANISM(S): Homo Sapiens 
PXD042977 |
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